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Table 3 Association between baseline obesity parameters and all-cause mortality in stage 3–4 chronic kidney disease. Comparison performed using Cox proportional hazards modelling to compare body mass index, waist circumference and conicity index with all-cause mortality

From: Association of anthropometric measures with kidney disease progression and mortality: a retrospective cohort study of pre-dialysis chronic kidney disease patients referred to a specialist renal service

  

HR (95 % CI)

No. (%)

Crude

Model 1

Model 2

Model 3

Body mass index (kg/m2)

 <18.5

15 (1.8)

0.23 (0.03-1.67)

0.39 (0.05-2.89)

0.49 (0.07-3.58)

1.03 (0.14-7.80)

 18.5-24.9

174 (20.7)

1.00 (referent)

1.00 (referent)

1.00 (referent)

1.00 (referent)

 25-29.9

293 (34.8)

0.56 (0.37-0.86)**

.54 (0.35-0.83)**

0.57 (0.36-0.90)*

0.50 (0.30-0.83)**

 30-39.9

288 (34.2)

0.53 (0.34-0.82)**

.63 (0.41-0.98)*

0.70 (0.44-1.11)

0.69 (0.41-1.15)

 ≥40

72 (8.6)

0.86 (0.49-1.54)

1.40 (0.77-2.54)

1.71 (0.93-3.16)

1.74 (0.89-3.40)

Waist circumference tertiles (cm)

 M: <98.5, F < 90

197 (33.2)

1.00 (referent)

1.00 (referent)

1.00 (referent)

1.00 (referent)

 M: 98.5-110, F: 90-101

198 (33.3)

1.21 (0.75-1.95)

1.04 (0.65-1.68)

1.18 (0.72-1.95)

0.90 (0.52-1.58)

 M > 110, F: >101

199 (33.5)

0.83 (0.50-1.40)

1.07 (0.59-1.71)

1.09 (0.62-1.92)

1.00 (0.54-1.86)

Conicity index tertiles

 <1.291

196 (33.3)

1.00 (referent)

1.00 (referent)

1.00 (referent)

1.00 (referent)

 1.291-1.372

196 (33.3)

1.61 (0.93-2.77)

1.29 (0.75-2.22)

1.33 (0.74-2.36)

1.67 (0.89-3.13)

 >1.372

196 (33.3)

1.85 (1.09-3.15)*

1.57 (0.92-2.67)

1.53 (0.84-2.79)

1.31 (0.66-2.58)

  1. Results expressed as number (percentage) and hazard ratio (95 % confidence interval)
  2. Model 1: Adjusted for age
  3. Model 2: Adjusted for age, gender, race (Caucasian vs. Non-Caucasian)
  4. Model 3: Model 2 + estimated glomerular filtration rate, proteinuria, cause of chronic kidney disease, diabetes status
  5. *P ≤ 0.05, **P ≤ 0.01