| |
Classified by tertile of SD of HbA1c
|
Classified by tertile of SD of FPG
|
|---|
|
First tertile group (n = 79)
|
Second tertile group (n = 80)
|
Third tertile group (n = 80)
|
P value
|
First tertile group (n = 79)
|
Second tertile group (n = 80)
|
Third tertile group (n = 80)
|
P value
|
|---|
|
Age (year)a
|
65.97 ± 5.52
|
64.36 ± 7.30
|
64.88 ± 5.74
|
0.253
|
65.27 ± 6.09
|
64.71 ± 6.08
|
65.23 ± 6.62
|
0.825
|
|
Sex, female (%)b
|
36 (45.57)
|
42 (52.50)
|
47 (58.75)
|
0.252
|
41 (50.00)
|
47 (59.49)
|
37 (47.44)
|
0.279
|
|
BMI (kg/m2)a
|
24.43 ± 2.94
|
23.58 ± 2.71
|
23.79 ± 2.81
|
0.147
|
23.89 ± 2.89
|
23.44 ± 2.75
|
24.46 ± 2.79
|
0.074
|
|
SBP (mm Hg)a
|
152.92 ± 11.85
|
153.01 ± 8.71
|
156.02 ± 8.99
|
0.083
|
152.35 ± 8.16
|
153.56 ± 9.70
|
156.03 ± 11.61
|
0.061
|
|
DBP (mm Hg)a
|
83.68 ± 9.54
|
80.81 ± 7.73
|
82.92 ± 7.08
|
0.073
|
83.06 ± 8.34
|
82.38 ± 7.35
|
81.96 ± 8.99
|
0.701
|
|
Heart rate (bpm)a
|
74.82 ± 9.65
|
76.01 ± 9.09
|
74.34 ± 8.89
|
0.498
|
74.65 ± 10.78
|
75.30 ± 7.30
|
75.23 ± 9.31
|
0.888
|
|
Duration of diabetes (years)c
|
3.00 (2.85, 3.25)
|
3.00 (2.85, 3.27)
|
3.00 (2.82, 3.33)
|
0.905
|
3.00 (2.90, 3.35)
|
3.00 (2.69, 3.13)
|
3.00 (2.93, 3.19)
|
0.342
|
|
Current smoking, n (%)b
|
8 (10.13)
|
9 (11.25)
|
7 (8.75)
|
0.871
|
8 (9.76)
|
8 (10.13)
|
8 (10.26)
|
0.994
|
|
Current drinking, n (%)b
|
5 (6.33)
|
6 (7.50)
|
5 (6.25)
|
0.940
|
7 (8.54)
|
3 (3.80)
|
6 (7.69)
|
0.442
|
|
Hypertension history, n (%)b
|
62 (78.48)
|
60 (75.00)
|
65 (81.25)
|
0.631
|
64 (78.05)
|
61 (77.22)
|
62 (79.49)
|
0.941
|
|
FPG (mmol/L)a
|
9.80 ± 1.50
|
9.80 ± 1.57
|
10.14 ± 1.54
|
0.269
|
9.97 ± 1.43
|
9.99 ± 1.46
|
9.78 ± 1.72
|
0.625
|
|
HbA1c (%)a
|
10.01 ± 2.00
|
10.17 ± 1.53
|
10.62 ± 1.34
|
0.061
|
10.21 ± 1.44
|
10.19 ± 1.76
|
10.40 ± 1.77
|
0.684
|
|
TCHO (mmol/L)a
|
5.10 ± 0.99
|
5.36 ± 0.96
|
5.39 ± 1.00
|
0.127
|
5.41 ± 0.91
|
5.27 ± 0.96
|
5.18 ± 1.08
|
0.332
|
|
TG (mmol/L)a
|
1.89 ± 1.11
|
1.61 ± 0.84
|
1.73 ± 1.01
|
0.200
|
1.65 ± 0.88
|
1.65 ± 0.88
|
1.92 ± 1.18
|
0.139
|
|
HDL-c (mmol/L)a
|
1.37 ± 0.45
|
1.41 ± 0.48
|
1.38 ± 0.50
|
0.893
|
1.38 ± 0.50
|
1.36 ± 0.41
|
1.42 ± 0.52
|
0.768
|
|
LDL-c (mmol/L)a
|
3.35 ± 1.15
|
3.63 ± 1.11
|
3.67 ± 1.21
|
0.167
|
3.70 ± 1.08
|
3.58 ± 1.03
|
3.38 ± 1.33
|
0.215
|
|
Hypoglycemic agents, n (%)b
| | | | | | | | |
|
Metformin
|
73 (92.41)
|
72 (90.00)
|
75 (93.75)
|
0.675
|
74 (90.24)
|
74 (93.67)
|
72 (92.31)
|
0.720
|
|
Gliclazide
|
39 (49.37)
|
34 (42.50)
|
35 (43.75)
|
0.653
|
37 (45.12)
|
36 (45.57)
|
35 (44.87)
|
0.996
|
|
Other sulfonylurea
|
24 (30.38)
|
21 (26.25)
|
22 (27.50)
|
0.839
|
22 (26.83)
|
18 (22.78)
|
27 (34.62)
|
0.245
|
|
Thiazolidinedione
|
7 (8.86)
|
5 (6.25)
|
8 (10.00)
|
0.681
|
11 (13.41)
|
4 (5.06)
|
5 (6.41)
|
0.120
|
|
Acarbose
|
15 (18.99)
|
15 (18.75)
|
11 (13.75)
|
0.613
|
19 (23.17)
|
12 (15.19)
|
10 (12.82)
|
0.189
|
|
Glinide
|
4 (5.06)
|
4 (5.00)
|
3 (3.75)
|
0.905
|
5 (6.10)
|
4 (5.06)
|
2 (2.56)
|
0.551
|
|
Insulin
|
9 (11.39)
|
7 (8.75)
|
7 (8.75)
|
0.809
|
8 (9.76)
|
8 (10.13)
|
7 (8.97)
|
0.969
|
|
Other drugs, n (%)b
| | | | | | | | |
|
Antihypertension drug
|
57 (72.15)
|
56 (70.00)
|
63 (79.63)
|
0.425
|
58 (70.73)
|
58 (73.42)
|
60 (76.92)
|
0.673
|
|
Aspirin
|
56 (70.89)
|
49 (61.25)
|
43 (53.75)
|
0.084
|
51 (62.20)
|
47 (59.49)
|
50 (64.10)
|
0.836
|
|
Statins
|
11 (13.92)
|
13 (16.25)
|
11 (13.75)
|
0.883
|
12 (14.63)
|
12 (15.19)
|
11 (14.10)
|
0.982
|
- Results are means ± SDs or medians (25th, 75th percentiles) for continuous variables and numbers (percentages) for categorical variables
- SD standard deviation, HbA1c hemoglobin A1c, BMI body mass index, SBP systolic blood pressure, DBP diastolic blood pressure, FPG fasting plasma glucose, TCHO total cholesterol, TG triglycerides, HDL-c high-density lipoprotein cholesterol, LDL-c low-density lipoprotein cholesterol
- acompared using ANOVA with Bonferroni procedure
- bcompared using Chi-square test
- ccompared using Kruskal-Wallis test
