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Table 3 HbA1c and FPG profiles and severe hypoglycemic episodes during follow-up period

From: Excessive visit-to-visit glycemic variability independently deteriorates the progression of endothelial and renal dysfunction in patients with type 2 diabetes mellitus

  Classified by tertile of SD of HbA1c Classified by tertile of SD of FPG
  First tertile group (n = 79) Second tertile group (n = 80) Third tertile group (n = 80) P value First tertile group (n = 79) Second tertile group (n = 80) Third tertile group (n = 80) P value
Mean HbA1c (%) 8.22 ± 1.00 8.33 ± 0.79 8.11 ± 0.56 0.213 8.07 ± 0.65 8.23 ± 0.72 8.35 ± 0.99 0.093
SD of HbA1c (%) 1.41 ± 0.50 2.68 ± 0.36* 3.52 ± 0.47*,** <0.001 2.05 ± 0.92 2.64 ± 0.81* 2.93 ± 0.99* <0.001
CV of HbA1c (%) 17.66 ± 4.59 32.48 ± 3.68* 43.89 ± 4.49*,** <0.001 26.31 ± 9.60 32.21 ± 9.26* 32.75 ± 10.63* <0.001
Mean FPG (mmol/L) 6.98 ± 0.97 6.92 ± 0.86 6.70 ± 0.55 0.075 6.76 ± 0.64 6.83 ± 0.74 7.02 ± 0.98 0.106
SD of FPG (mmol/L) 3.49 ± 1.27 3.70 ± 0.91 4.26 ± 1.24*,** <0.001 2.69 ± 0.48 3.68 ± 0.28* 5.09 ± 0.95*, ** <0.001
CV of FPG (%) 50.10 ± 8.62 53.68 ± 7.80* 63.87 ± 8.27*,** <0.001 39.81 ± 5.34 53.87 ± 6.29* 72.52 ± 8.56*, ** <0.001
Severe hypoglycemic episodes (times) 0.70 ± 0.64 1.09 ± 0.79* 1.94 ± 1.63*,** <0.001 1.02 ± 1.08 1.32 ± 1.22 1.40 ± 1.33 0.112
  1. Results are means ± SDs
  2. SD standard deviation, CV coefficient of variation, HbA1c hemoglobin A1c, FPG fasting plasma glucose
  3. *P < 0.05, as compared to first tertile group in the same classified groups
  4. **P < 0.05, as compared to second tertile group in the same classified groups