Coronary Artery Disease | No Coronary Disease | |||||
---|---|---|---|---|---|---|
Overall | Smoking Status | Smoking Status | ||||
Yes | No | Yes | No | |||
(n = 19,271) | (n = 295,192) | 49,459 | 856,020 | |||
Demographics | ||||||
Age (years) | 62.8 (15.3) | 63 (11.3) | 69.6 (11.2)* | 54.3 (13.8) | 60.9 (15.9)* | |
Gender (%) | ||||||
Male | 54.3 | 66.5 | 57.9* | 63.3 | 52.3* | |
Race (%) | ||||||
White | 65.4 | 77.3 | 77.6 | 59.9 | 61.2* | |
Black | 29.7 | 20.3 | 18.4* | 37.4 | 33.4* | |
Asian | 3.8 | 1.1 | 2.9* | 1.5 | 4.3* | |
Native American | 1.11 | 1.3 | 1* | 1.2 | 1.2 | |
Hispanic (%) | ||||||
Hispanic | 7.8 | 2.8 | 6.6* | 3 | 8.6* | |
Comorbid Conditions (%) | ||||||
Diabetes (cause of ESKD)a | 45.3 | 45.3 | 53.5* | 33.3 | 43.2* | |
Diabetes (as comorbid condition) | 52.8 | 55.3 | 62.9* | 40.4 | 50* | |
Hypertension | 79.4 | 88.8 | 83.8* | 84 | 77.4* | |
Heart Failure | 33.1 | 57.3 | 59.2* | 24.2 | 24.1 | |
Coronary Disease | 25.8 | |||||
Stroke | 9.5 | 20.8 | 16.2* | 8.9 | 7* | |
Peripheral Arterial Disease | 14.7 | 43.2 | 30.8* | 13.4 | 8.5* | |
Chronic lung disease | 8.2 | 41.2 | 13* | 18.7 | 5.1* | |
Malignancy | 6.4 | 7.6 | 7.3 | 6.4 | 6 | |
Body Mass Index (kg/m2) | 27.5 (7.3) | 26 (6.7) | 27.3 (6.9)* | 26.1 (7.1) | 27.7 (7.5)* | |
Lifestyle factors (%) | ||||||
Alcohol Dependence | 1.5 | 6.1 | 0.7* | 10.6 | 1.2* | |
Drug dependence | 1.2 | 2.7 | 0.3* | 8.6 | 1* | |
Functional Status (%) | ||||||
Inability to walk independently | 5.2 | 8.2 | 8 | 4.4 | 4.2 | |
Inability to transfer independently | 2.1 | 2.6 | 3.2* | 1.4 | 1.8* | |
Employment Status (%) | ||||||
Full time employment | 8.2 | 4.5 | 3.4* | 9.7 | 9.8 | |
Part time employment | 1.8 | 1.4 | 1.1* | 2.2 | 2* | |
Unemployed | 19.8 | 16.6 | 11.5* | 31.1 | 22* | |
Homemaker | 4.8 | 3.5 | 5.2* | 3 | 4.9* | |
Retired from age | 39.8 | 39.1 | 55.6* | 20.8 | 35.4* | |
Retired from disability | 19.4 | 29.7 | 18.9* | 26.5 | 18.9* | |
Medical leave of absence | 3.0 | 2.4 | 1.4* | 4.3 | 3.5* | |
Student | 0.29 | 0.03 | 0.02 | 0.2 | 0.4* | |
Other | 3.0 | 2.6 | 2.7 | 2.2 | 3.1* | |
Laboratory Variables | ||||||
Serum Creatinine (μmol/L) | 654.2 (309.4) | 601.7 (251.4) | 560.9 (226.4)* | 726.3 (351.9) | 681.2 (330.4)* | |
eGFRb (ml/min/1.73 m2) | 8.6 (3.8) | 8.8 (3.7) | 8.8 (3.6) | 8.0 (3.8) | 7.9 (3.6)* | |
Albumin (g/L) | 31 (7.0) | 31 (6.6) | 31.3 (6.4)* | 3.1 (0.7) | 3.1 (0.7)* | |
Pre-ESRD Care (%) | ||||||
Erythropoietin use | 29.0 | 27.4 | 32.2* | 23.2 | 28.3* | |
Dialysis Modality at day 90 (%) | ||||||
Peritoneal Dialysis | 7.0 | 6.5 | 5.3* | 7.9 | 7.5 | |
Hemodialysis | 80.4 | 79.6 | 78.7 | 81.4 | 80.9 |