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Table 2 Characteristics of patients with and without Stroke and Peripheral Arterial Disease by Smoking Status at dialysis initiation

From: Differential impact of smoking on mortality and kidney transplantation among adult Men and Women undergoing dialysis

  

Stroke

No Stroke

Peripheral Arterial Disease

No Peripheral Arterial Disease

  

Smoking Status

Smoking Status

Smoking Status

Smoking Status

  

Yes

No

Yes

No

Yes

No

Yes

No

  

(n = 8,384)

(n = 107, 806)

60,339

1,043,406

(n = 14, 960)

(n = 163, 846)

53,763

987,379

Demographics

 

Age (years)

61.9 (11.7)

68.4 (12)*

56 (13.8)

62.6 (15.5)*

63.1 (11.3)

68.1 (11.9)*

55 (13.8)

62.3 (15.7)*

Gender (%)

 

Male

63.3

52.5*

64.3

53.9*

65.4

57.9*

63.9

53.1*

Race (%)

 

White

69.1

66.2*

64.2

65.3*

79

76.2*

60.9

63.6*

 

Black

28.6

29.5

33.1

29.6*

18.8

20.3*

36.4

31.1*

 

Asian

1.1

3.3*

1.4

4*

0.8

2.1*

1.6

4.2*

 

Native American

1.3

0.9

1.2

1.1

1.4

1.4

1.2

1.1

Hispanic (%)

 

Hispanic

2.3

5.8*

3.1

8.3*

2.8

7.2*

3

8.2*

Comorbid Conditions (%)

 

Diabetes (cause of ESKD)a

44

52.1*

35.6

45.2*

48.5

59.4*

33.4

43.5*

 

Diabetes (comorbid condition)

54

61.8*

43.3

52.4*

57.9

68*

40.9

50.9*

 

Hypertension

91.1

87.2*

84.5

78.2*

89.7

85.8*

84.1

77.9*

 

Heart Failure

45

46.8

31.9

31.7

52

56.9*

28.3

29.1*

 

Coronary Disease

47.7

44.3*

25.3

23.7*

55.6

55.4

20.4

20.7

 

Stroke

    

22.4

19.5*

9.4

7.7*

 

Peripheral Arterial Disease

40

29.6*

19.2

12.6*

    
 

Chronic lung disease

35.7

11.9*

23.5

6.7*

43.6

14.2*

19.8

6*

 

Malignancy

8

7.3

6.5

6.2

7.4

6.1*

6.5

6.4

 

Body Mass Index (kg/m2)

25.5 (6.6)

26.8 (6.8)*

26.2 (7)

27.7 (7.4)*

25.6 (6.7)

27.4 (7.3)*

26.2 (7)

27.6 (7.4)*

Lifestyle factors (%)

 

Alcohol Dependence

8.2

1.0*

9.5

1.1*

6.1

0.8*

10.3

1.1*

 

Drug dependence

4.2

0.6*

7.4

0.8*

2.7

0.4*

8.2

0.9*

Functional Status (%)

 

Inability to walk independently

11.5

13.6*

4.6

4.3*

11.3

11.9

3.8

4

 

Inability to transfer independently

4.3

6.5*

1.4

1.7*

3.5

4.8*

1.2

1.7*

Employment Status (%)

 

Full time employment

3

2.2*

9

8.8

4

3.1*

9.4

9*

 

Part time employment

0.8

0.7

2.2

1.9*

1.4

1*

2.2

1.9*

 

Unemployed

19.6

14.1*

28.1

19.9*

16.1

13.3*

30.1

20.3*

 

Homemaker

3.6

5*

3.1

4.9*

3.6

4.9*

3

4.9*

 

Retired from age

35.8

51.2*

24.6

39.5*

39.3

51.3*

22.2

38.8*

 

Retired from disability

33

23.3*

26.6

18.5*

31.2

22.3*

26.4

18.4*

 

Medical leave of absence

1.9

1.2*

4

3.1*

2

1.3*

4.3

3.2*

 

Student

0.05

0.05

0.1

0.3*

0.03

0.04

0.2

0.3*

 

Other

2.3

2.4

2.3

3.1*

2.4

2.7

2.3

3.1*

Laboratory Variables

 

Serum Creatinine (μmol/L)

616 (259)

580 (244)*

702 (340)

658 (317)*

594 (248)

564 (228)*

719 (347)

665 (321)*

 

eGFRb (ml/min/1.73 m2)

8.7 (3.7)

8.6 (3.6)

8.1 (3.8)

8.1 (3.7)*

8.9 (3.8)

8.9 (3.7)

8 (3.8)

8 (3.6)

 

Albumin (g/L)

30.7 (6.7)

30.9 (6.6)

3.1 (0.7)

3.1 (0.7)*

30.6 (6.8)

30.7 (6.6)

3.1 (0.7)

3.2 (0.7)*

Pre-ESRD Care (%)

 

Erythropoietin use pre-dialysis

25.6

30.1*

24.2

29.2*

28.2

32.7*

23.3

28.7*

Dialysis Modality at day 90 (%)

 

Peritoneal Dialysis

5.9

4.5*

7.7

7.2*

6.2

4.9*

7.8

7.3*

 

Hemodialysis

80.4

79.8

81

80.4*

79.5

79.2

81.3

80.6*

  1. All values are reported as % or means with standard deviation
  2. aESKD: end-stage kidney disease
  3. bGlomerular filtration rate (ml/min per 1.73 m2) was based on the Chronic Kidney Disease Epidemiology Collaboration [25]
  4. *P < 0.001 for all bivariate comparisons