Table 5 Health-related quality of life scores by erythropoiesis stimulating agent/supplemental iron use in patients with CKD stages 3 and 4 and those on dialysis
Subscales of the KDQOL-36 | No ESA/supplemental iron use Mean (SD) | ESA and/or supplemental iron use Mean (SD) | P-value |
|---|---|---|---|
Symptoms/problems list | 83.5 (17.1) | 77.1 (17.6) | <0.0001 |
Effect of Kidney Disease | 76.9 (19.0) | 64.5 (21.0) | <0.0001 |
Burden of Kidney Disease | 61.5 (25.8) | 46.9 (25.8) | <0.0001 |
SF-12 physical composite summary | 42.4 (10.1) | 37.6 (9.5) | <0.0001 |
CKD stage 3 | 44.6 (9.3) | 40.8 (9.9) | 0.0019 |
CKD stage 4 | 40.5 (10.3) | 36.9 (8.9) | 0.0007 |
Dialysis | 39.0 (10.4) | 37.1 (9.7) | 0.1441 |
SF-12 mental composite summary | 47.9 (9.3) | 45.4 (10.1) | <0.0001 |
CKD stage 3 | 49.7 (8.6) | 46.9 (10.0) | 0.0206 |
CKD stage 4 | 46.9 (9.4) | 44.9 (9.8) | 0.0653 |
Dialysis | 44.3 (10.0) | 45.3 (10.3) | 0.4347 |