Long-term outcomes in antineutrophil cytoplasmic autoantibody–positive eosinophilic granulomatosis with polyangiitis patients with renal involvement: a retrospective study of 14 Chinese patients

Table 1 Clinic-pathological data of patients with EGPA and renal involvement

Case	Gender/Age range (years)	T1/T2 (months)	Onset symptom	Extra-renal involvement	Upro (g/24 h)	EOS (%)	IgE (g/l)	SCr (mg/dl)	Alb (g/l)	MPO-ANCA (RU/ml)	Renal class	Crescent (%)	GS (%)	Interstitial EOS	FPE
1	F/45-55	240/4	Asthma	N/NS	1.00	20	358	4.50	45.2	674.6	Mixed	39	49	+^b	NA
2	F/25-35	24/24	Hemoptysis	L/A/SK/N	0.10	45	217	1.47	32.4	343.5	AIN	0	0	+	NA
3	F/18-25	1/1	GH	N	7.80	16	976	11.00	27	20.0	Crescentic	90	0	+	Extensive
4	F/55-65	600/28	Asthma	L/H/NS	0.97	31	1000	1.70	43.2	28.8	Mixed	40	27	+	NA
5	M/25-35	120/1	Asthma	L	1.14	10	316	1.68	41.7	86.3	Focal	19	25	−	Segmental
6	F/45-55	408/48	Asthma	L/SK	0.99	12	1000	5.90	34	161.0	Mixed	31	45	+	NA
7	M/65-75	120/1	Asthma	L	4.96	20	580	4.90	29	352.6	Crescentic	51	19	+	Extensive
8	F/55-65	2/1	Hemoptysis	L	0.50	10	200	10.50	34	180.0	Crescentic	80	0	+	Segmental
9	M/45-55	9/1	Arthritis	L/SK/A/N/E	0.53	21	287	9.40	37	156.4^a	Mixed	9	41	−	NA
10	M/25-35	36/36	GH	N	12.30	14	1000	3.90	28.2	109.5^a	Mixed	46	42	+	Extensive
11	M/55-65	240/1	Asthma	L/NS/N	0.50	20	567	6.09	29	101.5	Focal	16	16	+^b	NA
12	F/45-55	600/2	Asthma	L/N	5.32	11	243	2.74	26.5	222.0	Mixed	23	30.8	−	NA
13	M/45-55	1/1	Hemoptysis	L/H	1.78	13	271	8.68	33.2	207.3	Sclerotic	10	80	+	Segmental
14	F/45-55	240/1	Asthma	L	4.45	14	567	6.50	25.3	384.8	Crescentic	79	21	+^b	NA

EGPA eosinophilic granulomatosis with polyangiitis. T1 total duration, T2 duration of renal involvement, EOS eosinophilia, GS glomerular sclerosis, FPE foot process effacement, GH gross hematuria, SK skin, E eye, N sinusitis, A arthralgia, NS nervous system, L lung, H heart, AIN acute interstitial nephritis, ^aPR3-ANCA, ^beosinophilic granuloma, NA unavailable

ISSN: 1471-2369