Table 1 Comparison of patients who developed NODAT to those who did not

Number of patients (%)

333 (79.6)

85 (20.4)

Age (years)

40.85 ± 10.54

47.82 ± 10.75

<0.001

Sex, male (%)

176 (52.9)

53 (62.4)

0.143

BMI, pre-transplantation (kg/m²)

21.9 ± 3.0

24.1 ± 3.2

<0.001

BMI category, pre-transplantation(%)

  ≥ 18.5 kg/m²

293 (88.0)

84 (98.8)

0.004

  ≥ 25 kg/m²

50 (15.0)

35 (41.2)

<0.001

  ≥ 30 kg/m²

2 (0.6)

4 (4.7)

0.017

  ≥ 35 kg/m²

1 (0.3)

0 (0.0)

0.797

Weight change

 14 days (kg)

2.94 ± 3.54

3.51 ± 3.02

0.179

 3 months (kg)

0.67 ± 4.60

3.02 ± 4.87

0.002

Hypertension (%)

301 (90.4)

79 (92.9)

0.534

Prior kidney transplantation (%)

21 (6.3)

4 (4.7)

0.627

Donor Age (years)

41.9 ± 10.9

42.3 ± 10.6

0.805

Donor Sex, male (%)

181 (54.4)

41 (48.2)

0.332

Family history of diabetes mellitus (%)

 Any first degree relative

49 (14.7)

21 (24.7)

0.036

 One parent

38 (11.4)

12 (14.1)

0.147

 Both parents

2 (0.6)

1 (1.2)

1.000

 Sibling

9 (2.7)

8 (9.4)

0.126

Cold ischemic time (minute)

36.0 ± 19.6

40.0 ± 29.5

0.132

Rejection history within 1 year (%)

24 (7.2)

9 (10.6)

0.365

Polycystic kidney disease (%)

13 (3.9)

7 (8.2)

0.148

Immunosuppressive treatment

 Tacrolimus (%)

230 (68.9)

59 (69.4)

1.000

 Cyclosporine (%)

104 (31.1)

26 (30.6)

1.000

 Mycophenolate mofetil (%)

273 (81.7)

64 (75.3)

0.181

 Azathioprine (%)

30 (9.0)

11 (12.9)

0.306

 Corticosteroids (%)

315 (94.3)

83 (97.6)

0.273

 Tacrolimus level, 1 month (ng/mL)

8.40 ± 3.01

8.45 ± 3.22

0.924

 Tacrolimus level, 3 months (ng/mL)

7.45 ± 2.58

7.25 ± 2.63

0.599

 Cyclosporine level, 1 month (ng/mL)

216.1 ± 89.6

219.9 ± 91.1

0.854

 Cyclosporine level, 3 months (ng/mL)

180.9 ± 79.6

157.5 ± 63.7

0.189

 Corticosteroids dose, 1 month (mg)

14.6 ± 3.90

14.9 ± 6.85

0.667

 Corticosteroids total dose for 1 month (g)

1.96 ± 0.37

1.95 ± 0.50

0.912

 Corticosteroids dose, 3 months (mg)

10.3 ± 3.12

9.8 ± 3.08

0.187

 Corticosteroids total dose for 3 month (g)

2.65 ± 0.50

2.63 ± 0.61

0.802

Mg supplementation, pre-transplantation (%)

3 (0.9)

0 (0)

0.611

Serum magnesium level

 Pre-transplantation (mg/dL)

2.17 ± 0.35

2.22 ± 0.34

0.213

 7 days (mg/dL)

1.94 ± 0.21

1.97 ± 0.23

0.270

 1 month (mg/dL)

1.80 ± 0.23

1.81 ± 0.23

0.897

 3 month (mg/dL)

1.82 ± 0.22

1.84 ± 0.23

0.641

Glucose, pre-transplantation (mg/dL)

88.8 ± 10.4

95.7 ± 13.5

<0.001

Total cholesterol (mg/dL)

155.5 ± 35.7

161.9 ± 32.5

0.134

eGFR, 1 year (mL/min/1.73 m²)

64.7 ± 19.7

61.2 ± 17.7

0.152

eGFR, 3 years (mL/min/1.73 m²)

65.1 ± 21.5

59.4 ± 19.8

0.028