Table 3 Estimate of odds ratios, with the 95 % confidence limits
From: Proton pump inhibitors are associated with increased risk of development of chronic kidney disease
For Mortality outcome Odds Ratio Estimates | For CKD outcome Odds Ratio Estimates | ||||||||
|---|---|---|---|---|---|---|---|---|---|
Effect | Contract | Point Estimate | 95 % Wald Confidence Limits | p-value | Point Estimate | 95 % Wald Confidence Limits | p-value | ||
PPI | Yes vs No | 1.76 | 1.68 | 1.84 | <.0001 | 1.10 | 1.05 | 1.16 | <.0001 |
age | 1 year increase | 1.07 | 1.06 | 1.07 | <.0001 | 1.07 | 1.07 | 1.07 | <.0001 |
Race | Black vs White | 1.41 | 1.30 | 1.53 | <.0001 | 0.92 | 0.86 | 0.99 | 0.0269 |
Sex | Female vs Male | 0.62 | 0.54 | 0.72 | <.0001 | 1.32 | 1.20 | 1.45 | <.0001 |
Vascular Disease | Yes vs No | 1.52 | 1.45 | 1.59 | <.0001 | 0.94 | 0.89 | 0.98 | 0.009 |
COPD | Yes vs No | 2.41 | 2.28 | 2.54 | <.0001 | 0.97 | 0.91 | 1.04 | 0.378 |
Cancer | Yes vs No | 1.91 | 1.82 | 2.02 | <.0001 | 0.78 | 0.74 | 0.84 | <.0001 |
Diabetes | Yes vs No | 1.53 | 1.46 | 1.61 | <.0001 | 1.66 | 1.59 | 1.74 | <.0001 |
Hypertension | Yes vs No | 1.38 | 1.30 | 1.47 | <.0001 | 2.43 | 2.31 | 2.55 | <.0001 |
GI | Yes vs No | 1.03 | 0.98 | 1.08 | 0.25 | 0.99 | 0.94 | 1.04 | 0.6208 |
Time at risk | 1 quarter increase | 0.91 | 0.91 | 0.91 | <.0001 | 0.90 | 0.89 | 0.90 | <.0001 |