Table 4 Adjusted OD and 95 % confidence interval for CKD and Mortality outcomes associated with PPI for each subgroups
From: Proton pump inhibitors are associated with increased risk of development of chronic kidney disease
Subgroup | OR | CKD | Mortality | 95%CI | |||
|---|---|---|---|---|---|---|---|
95%CI | OR | ||||||
Age | <65 | 1.24 | 1.17 | 1.29 | 2.26 | 2.07 | 2.47 |
>65 | 1.21 | 0.89 | 1.69 | 1.60 | 1.51 | 1.70 | |
Gender | Female | 1.09 | 0.94 | 1.49 | 1.67 | 1.24 | 2.30 |
Male | 1.10 | 1.05 | 1.15 | 1.70 | 1.68 | 1.85 | |
Race | Black | 1.01 | 0.85 | 1.18 | 1.68 | 1.41 | 2.00 |
White | 1.16 | 1.06 | 1.17 | 1.77 | 1.68 | 1.86 | |
GI | Absent | 1.21 | 1.14 | 1.29 | 2.18 | 2.00 | 2.24 |
Present | 0.93 | 0.86 | 1.10 | 1.18 | 1.08 | 1.28 | |
DM | Absent | 1.11 | 1.05 | 1.17 | 1.70 | 1.60 | 1.80 |
Present | 1.07 | 0.99 | 1.18 | 1.89 | 1.74 | 2.06 | |
HTN | Absent | 1.21 | 1.09 | 1.34 | 1.63 | 1.44 | 1.85 |
Present | 1.07 | 1.01 | 1.12 | 1.78 | 1.69 | 1.87 | |
Vascular | Absent | 1.13 | 1.07 | 1.19 | 1.87 | 1.76 | 1.99 |
Present | 1.02 | 0.93 | 1.13 | 1.63 | 1.51 | 1.75 | |
Cancer | Absent | 1.10 | 1.05 | 1.16 | 1.70 | 1.61 | 1.80 |
Present | 1.11 | 0.96 | 1.28 | 1.90 | 1.72 | 2.11 | |