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Table 4 Adjusted OD and 95 % confidence interval for CKD and Mortality outcomes associated with PPI for each subgroups

From: Proton pump inhibitors are associated with increased risk of development of chronic kidney disease

Subgroup OR CKD Mortality 95%CI  
95%CI OR
Age <65 1.24 1.17 1.29 2.26 2.07 2.47
  >65 1.21 0.89 1.69 1.60 1.51 1.70
Gender Female 1.09 0.94 1.49 1.67 1.24 2.30
  Male 1.10 1.05 1.15 1.70 1.68 1.85
Race Black 1.01 0.85 1.18 1.68 1.41 2.00
  White 1.16 1.06 1.17 1.77 1.68 1.86
GI Absent 1.21 1.14 1.29 2.18 2.00 2.24
  Present 0.93 0.86 1.10 1.18 1.08 1.28
DM Absent 1.11 1.05 1.17 1.70 1.60 1.80
  Present 1.07 0.99 1.18 1.89 1.74 2.06
HTN Absent 1.21 1.09 1.34 1.63 1.44 1.85
  Present 1.07 1.01 1.12 1.78 1.69 1.87
Vascular Absent 1.13 1.07 1.19 1.87 1.76 1.99
  Present 1.02 0.93 1.13 1.63 1.51 1.75
Cancer Absent 1.10 1.05 1.16 1.70 1.61 1.80
  Present 1.11 0.96 1.28 1.90 1.72 2.11