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Table 2 Effect of addition of MRA on final visit blood pressure

From: Effect of mineralocorticoid receptor antagonists on proteinuria and progression of chronic kidney disease: a systematic review and meta-analysis

Variable Measurement No. of study groups No. patients in intervention No. patients in placebo/control Effect size (95 % CI) I2 (p value)
Systolic BP (mmHg) Change from baseline 9 260 266 −3.30 (−5.56, −1.04) 40.0 % (0.101)
Final visit 16 666 659 −5.69 (−9.04, −2.34) 81.8 % (0.000)
Diastolic BP (mmHg) Change from baseline 9 260 266 −2.84 (−3.35, −2.33) 0.0 % (0.799)
Final visit 16 666 659 −1.73 (−3.37, −0.10) 68.3 % (0.000)