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Table 2 The result of the most significant KEGG pathway in each functional group

From: Identification of potential candidate genes for hypertensive nephropathy based on gene expression profile

ID Pathway name Count p-value FDR Genes
00982 Drug metabolism 60 8.02E-43 1.93E-40 CYP3A4, ADH1A, FMO1, GSTA1, MAOA
00350 Tyrosine metabolism 29 1.36E-19 3.19E-17 ADH1A, COMT, DBH, FAH, GOT1
04510 Focal adhesion 79 3.98E-18 9.23E-16 ACTN1, ACTN2, COL4A1, EGF, VWF
00010 Glycolysis/Gluconeogenesis 38 4.46E-16 1.02E-13 ACSS1, DLAT, ENO2, FBP1, HK1
05146 Amoebiasis 49 6.08E-15 1.38E-12 ACTN1, CD14, FN1, IL10, TNF
00590 Arachidonic acid metabolism 35 8.03E-15 1.81E-12 ALOX12B, CYP2B6, CYP2B6, GGT1, CYP4A11
00280 Valine, leucine and isoleucine degradation 29 6.82E-14 1.53E-11 AACS, DLD, EHHADH, IL4I1, PCCB
00410 beta-Alanine metabolism 21 1.48E-11 3.22E-09 ABAT, ACADM, DPYD, EHHADH, UPB1
00051 Fructose and mannose metabolism 20 8.95E-10 1.87E-07 AKR1B1, FBP1, HK1, MPI, PFKFB1
05144 Malaria 22 2.04E-07 3.90E-05 CCL2, HGF, ICAM1, MET, VCAM1
04020 Calcium signaling pathway 47 1.59E-05 0.002881 ADCY2, BDKRB1, AGTR1, EDNRA, F2R
  1. KEGG Kyoto Encyclopedia of Genes and Genomes, FDR false discovery rate. The p-value is adjusted into FDR using the Bonferroni correction