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Table 1 Patient characteristics

From: Prognosis of patients with severe hyponatraemia is related not only to hyponatraemia but also to comorbidities and to medical management: results of an observational retrospective study

 

All patients

(n = 147)

Group A

(n = 20)

Group B

(n = 41)

Group C

(n = 86)

P a

Age (years)

n = 147

69.6 ± 13.3

68.8 ± 14.5

69.5 ± 13.2

69.9 ± 13.3

.95

Males/Females (%)

n = 147

42.2/57.8

35.0/65.0

48.8/51.2

40.7/59.3

.57

Weight (kg)

n = 116

64.6 ± 16.5

62.3 ± 14.6

67.8 ± 18.0

63.4 ± 16.1

.39

BMI (kg/m2)

n = 79

24.1 ± 5.8

22.0 ± 5.1

25.2 ± 7.2

24.0 ± 5.1

.37

Plasma sodium at admission (mmol/l)

n = 147

121 ± 10.4

110 ± 11.7

119 ± 8.4

126 ± 8.5

<.001

Nadir plasma sodium (mmol/l)

n = 147

115 ± 4.7

105 ± 3.4

113 ± 1.4

118 ± 1.0

<.001

Measured plasma osmolality (mosm/l)

n = 50

254 ± 18

240 ± 13

252 ± 12

265 ± 18

<.001

Plasma sodium at discharge (mmol/l)

- Survivors

- Nonsurvivors

n = 111

n = 36

132 ± 6.5

132 ± 11.2

133 ± 8.6

124 ± 18.4

134 ± 8.9

133 ± 13.8

131 ± 7.2

132 ± 9.1

.24

.61

Delta plasma sodium (mmol/l) b

n = 147

20.8 ± 8.6

31.1 ± 6.5

23.0 ± 8.2

17.4 ± 6.9

<.001

Serum potassium (mmol/l)

n = 147

4.2 ± 1.0

3.8 ± 1.0

4.0 ± 0.9

4.4 ± 1.0

.01

Urea (mmol/l)

n = 147

10.1 ± 10.4

7.0 ± 9.6

8.4 ± 9.1

11.7 ± 10.9

.02

Plasma creatinine (μmol/l)

n = 147

118 ± 134

83 ± 115

93 ± 84

138 ± 153

.03

eGFR (ml/min/1.73 m2)

n = 147

100 ± 65.1

131 ± 65.3

100 ± 58.7

93 ± 66.5

.05

Uric acid (μmol/l)

n = 59

336 ± 237

258 ± 261

285 ± 246

386 ± 220

.04

Plasma glucose (g/l)

n = 143

1.54 ± 1.16

1.50 ± 0.58

1.32 ± 0.90

1.66 ± 1.35

.08

Triglycerides (g/l)

n = 40

0.83 ± 0.33

0.73 ± 0.30

0.88 ± 0.30

0.85 ± 0.40

.51

Total protein (g/l)

n = 100

62 ± 8.3

62 ± 6.1

63 ± 9.3

62 ± 8.4

.89

Serum albumin (g/l)

n = 110

34 ± 6.0

36 ± 3.9

35 ± 5.7

33 ± 6.6

.19

TSH

n = 72

3.66 ± 9.1

1.71 ± 2.58

3.73 ± 10.31

4.47 ± 10.2

.03

Plasma cortisol

n = 26

230 ± 106

247 ± 95

191 ± 75

240 ± 122

.59

BNP

n = 55

453 ± 586

537 ± 331

382 ± 545

472 ± 646

.27

  1. Group A: plasma sodium <110 mmol/l; group B: plasma sodium 110–115 mmol/l; group C: plasma sodium 116–120 mmol/l. BMI Body Mass Index, eGFR estimated Glomerular Filtration Rate, TSH Thyroid Stimulating Hormone, BNP Brain Natriuretic Peptide. abetween group A, B and C. bDelta plasma sodium is the difference between the highest and the lowest plasma sodium during hospitalisation
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BMC Nephrology

ISSN: 1471-2369

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