Skip to main content
Fig. 6 | BMC Nephrology

Fig. 6

From: Granulocyte colony-stimulating factor treatment ameliorates lupus nephritis through the expansion of regulatory T cells

Fig. 6

G-CSF treatment decreased numbers of CD11b+Ly6G+Ly6Clow and CD11b+Ly6G-Ly6Chigh myeloid cells. a Flow cytometric dot plots for Ly6G and Ly6C defined CD11b+Ly6G+Ly6Clow and CD11b+Ly6G-Ly6Chigh cells in spleen (CD11b+ gated). Bar graphs on the left side showed proportions of CD11b+Ly6G+Ly6Clow and CD11b+Ly6G-Ly6Chigh cells among total splenocytes. Bar graphs on the right side indicated absolute numbers of CD11b+Ly6G+Ly6Clow and CD11b+Ly6G-Ly6Chigh cells in spleen. b Flow cytometric dot plots for Ly6G and Ly6C defined CD11b+Ly6G+Ly6Clow and CD11b+Ly6G-Ly6Chigh cells in kidney (CD45+CD11b+ gated). Bar graphs on the left side showed proportions of CD11b+Ly6G+Ly6Clow and CD11b+Ly6G-Ly6Chigh cells among renal CD45+ cells. Bar graphs on the right side indicated absolute numbers of CD11b+Ly6G+Ly6Clow and CD11b+Ly6G-Ly6Chigh cells in kidney. The data are expressed as the mean ± standard error of the mean, with n = 4 − 5 mice per group. White and black bars indicate the G-CSF group and the PBS group, respectively. *P < 0.05, **P < 0.01 for comparisons between the G-CSF and the PBS groups using t-test. G-CSF: granulocyte colony-stimulating factor; PBS: phosphate-buffered saline; Tregs: regulatory T cells

Back to article page