Fig. 5From: Alteration of histone H3K4 methylation in glomerular podocytes associated with proteinuria in patients with membranous nephropathyPodocyte swelling and the expression of H3K4 me3 and synaptopodin in the LPS model. Electron microscopy reveals podocyte swelling induced by LPS administration (right side in a and d) compared with the controls (vehicle alone, left side in a and d). The expression of histone H3K4 me3 was significantly higher following LPS administration (right side in b and e) than in the controls (vehicle alone, left side in b and e). Synaptopodin expression was significantly lower following LPS administration (right side in c and f) compared to that of the controls (vehicle alone, left side in c and f). *P < 0.05 vs. Veh. LPS, lipopolysaccharide treated mice; Veh, vehicle treated mice; H3K4 me3, histone H3K4 trimethylation; N = 10. Data are expressed as the mean ± SEBack to article page