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Fig. 8 | BMC Nephrology

Fig. 8

From: Alteration of histone H3K4 methylation in glomerular podocytes associated with proteinuria in patients with membranous nephropathy

Fig. 8

Effect of MLL3 shRNA on synaptopodin expression and podocyte swelling in the LPS model. LPS-induced decreased synaptopodin expression was significantly restored by MLL3 shRNA compared with control shRNA as detected by immunohistochemistry (a and b). Electron microscopy showed the suppressive effect of MLL3 shRNA on LPS-induced podocyte swelling (c and d). *P < 0.05 vs. control shRNA. LPS, lipopolysaccharide treated mice; Cont, control; N = 10. Data are expressed as the mean ± SE

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