Table 1 Clinical findings at biopsy and follow-up visits in patients with psoriasis and membranous nephropathy
From: PLA2R antibodies and PLA2R glomerular deposits in psoriasis patients with membranous nephropathy
Case | Gender | Duration of psoriasis(m) | Duration of kidney disease(m) | Upro (g/24 h) | RBC (×104/ml) | Serum Alb (g/L) | SCr (mg/dl) | eGFR (ml/min/1.73 m2) | Anti-PLA2R antibody | Treatment | Outcome |
|---|---|---|---|---|---|---|---|---|---|---|---|
1 | M | 36 | 36 | 3.95 | 1 | 29.7 | 0.64 | 143.95 | - | Pred + TwHF | CR |
2 | M | 60 | 4 | 7.71 | 1 | 29.9 | 0.87 | 107.95 | - | TwHF | CR |
3 | M | 12 | 2 | 2.9 | 1 | 37.9 | 0.85 | 122.82 | - | TwHF | CR |
4 | F | 96 | 48 | 1.11 | 1 | 39.3 | 0.73 | 118.94 | - | FK506 | CR |
5 | M | 24 | 2.33 | 5.97 | 35 | 21 | 0.61 | 138.79 | - | TwHF,CsA | CR |
6 | M | 36 | 12 | 0.74 | 1 | 45.9 | 0.9 | 109.49 | - | TwHF | CR |
7 | F | 84 | 2 | 5.44 | 1 | 21.2 | 0.52 | 126.83 | - | NA | LOST |
8 | M | 60 | 2 | 4.78 | 1 | 21.9 | 1.31 | 55.16 | - | NA | LOST |
9 | F | 120 | 3 | 0.59 | 1 | 38.7 | 0.48 | 128.39 | - | Pred + TwHF | CR |
10 | M | 12 | 2 | 9.3 | 1 | 25.9 | 0.73 | 114.41 | - | TwHF | CR |
11 | M | 180 | 6 | 7.43 | 1 | 24.6 | 1.31 | 64.38 | - | Pred + TwHF | CR |
12 | M | 4 | 1.33 | 4.91 | 34 | 23.5 | 0.71 | 100.55 | + | TwHF | ESRD |
13 | M | 12 | 1 | 4.24 | 1 | 24.1 | 1.09 | 89.33 | + | Pred + TwHF | PR |
14 | M | 120 | 0.33 | 4.96 | 1 | 21.7 | 0.81 | 112.74 | - | Pred + TwHF | CR |
15 | M | 240 | 108 | 8.29 | 1 | 25.4 | 1.01 | 81.04 | + | TwHF | PR |
16 | M | 24 | 2 | 2.5 | 1 | 37.9 | 0.68 | 110.58 | - | TwHF | CR |
17 | M | 216 | 2 | 0.63 | 1 | 44.9 | 0.85 | 108.23 | - | TwHF | CR |
18 | M | 360 | 1 | 1.09 | 27 | 37.7 | 0.91 | 89.38 | + | TwHF | CR |
19 | M | 48 | 3 | 5.23 | 1 | 30.7 | 0.8 | 122.43 | + | Pred + TwHF | NR |
20 | M | 120 | 15 | 9.42 | 1 | 17.8 | 2.18 | 31.97 | + | Pred + TwHF | NR |
21 | M | 60 | 0.3 | 8.42 | 74 | 19.2 | 1.55 | 51.43 | + | NA | LOST |
22 | M | 240 | 0.25 | 5.47 | 8 | 20.5 | 1.12 | 76.18 | - | FK506 + Pred | CR |
23 | M | 480 | 1 | 8.67 | 10 | 19.8 | 1.02 | 75.7 | - | NA | LOST |
24 | M | 480 | 4 | 6.02 | 1 | 18.8 | 2.09 | 32.94 | - | NA | LOST |