Table 3 Distribution of renal biopsy diagnoses among elderly and younger adult patients with nephrotic range proteinuria
From: Kidney disease in the elderly: biopsy based data from 14 renal centers in Poland
| Â | Nephrotic range proteinuria with hematuria | P | Nephrotic range proteinuria without hematuria | P | Nephrotic range proteinuria with or without hematuria | P | |||
|---|---|---|---|---|---|---|---|---|---|
Renal pathology | ≥65 (n = 73) | 18–64 (n = 461) | ≥65 (n = 115) | 18–64 (n = 453) | ≥65 (n = 188) | 18–64 (n = 916) | |||
MGN | 22 (30.1%) | 49 (10.6%) | <0.001 | 25 (21.7%) | 106 (23.4%) | 0.804 | 47 (25.0%) | 155 (16.9%) | 0.013 |
FSGS | 15 (20.6%) | 79 (17.1%) | 0.508 | 23 (20.0%) | 81 (17.9%) | 0.591 | 38 (20.2%) | 160 (17.5%) | 0.404 |
Amyloidosis | 9 (12.3%) | 13 (2.8%) | 0.001 | 29 (25.2%) | 44 (9.7%) | <0.001 | 38 (20.2%) | 57 (6.2%) | <0.001 |
Pauci immune GN crescentic GN focal segmental GN | 7 (9.6%) 3 (4.1%) 4 (5.5%) | 31 (6.7%) 18 (3.9%) 13 (2.8) | 0.336 1.000 0.271 | 3 (2.6%) 1 (0.9%) 2 (1.7%) | 4 (0.9%) 2 (0.4%) 2 (0.4%) | 0.151 0.493 0.184 | 10 (5.3%) 4 (2.1%) 6 (3.2%) | 35 (3.8%) 20 (2.2%) 15 (1.6%) | 0.317 1.000 0.151 |
IgAN | 6 (8.2%) | 114 (24.7%) | 0.001 | 4 (3.5%) | 39 (8.6%) | 0.075 | 10 (5.3%) | 154 (16.8%) | <0.001 |
MCD | 5 (6.9%) | 30 (6.5%) | 0.804 | 11 (9.6%) | 84 (18.5%) | 0.025 | 16 (8.5%) | 114 (12.5%) | 0.137 |
Membrano-proliferative GN | 5 (6.9%) | 30 (6.5%) | 0.804 | 1 (0.9%) | 11 (2.4%) | 0.475 | 6 (3.2%) | 41 (4.5%) | 0.553 |
DKD | 2 (2.7%) | 26 (5.6%) | 0.405 | 13 (11.3%) | 23 (5.1%) | 0.029 | 15 (8.0%) | 49 (5.4%) | 0.170 |
LN | 1 (1.4%) | 51 (11.1%) | 0.005 | 0 | 23 (5.1%) | 0.007 | 1 (0.5%) | 74 (8.1%) | <0.001 |
End-stage kidney | 1 (1.4%) | 4 (0.9%) | 0.522 | 1 (0.9%) | 8 (1.8%) | 0.695 | 2 (1.1%) | 12 (1.3%) | 1.000 |
Arterionephrosclerosis | 1 (1.4%) | 2 (0.4%) | 0.357 | 1 (0.9%) | 5 (1.1%) | 1.000 | 2 (1.1%) | 7 (0.8%) | 0.655 |
MGA | 0 | 3 (0.7%) | 1.000 | 1 (0.9%) | 11 (2.4%) | 0.475 | 1 (0.5%) | 15 (1.6%) | 0.498 |
Thrombotic microangiopathy | 0 | 9 (2.0%) | 0.618 | 1 (0.9%) | 6 (1.3%) | 1.000 | 1 (0.5%) | 15 (1.6%) | 0.498 |
Unclassified lesions | 0 | 13 (2.8%) | 0.232 | 3 (2.6%) | 14 (3.1%) | 1.000 | 3 (1.6%) | 27 (3.0%) | 0.458 |