Table 1 Baseline Characteristics of Study Cohorts
All eligible patientsa N = 231,202 | Patients with pneumonia episodes while dialyzing at LDOb N = 39,988 | |
|---|---|---|
Age, years | ||
mean ± SD | 61.0 ± 15.3 | 64.6 ± 14.9 |
median (p25, p75) | 62 (51, 72) | 66 (55, 76) |
Sex, n (%) | ||
Male | 130,255 (56.4) | 21,602 (54.0) |
Female | 100,738 (43.6) | 18,383 (46.0) |
Race/Ethnicity, n (%) | ||
White | 105,733 (45.8) | 18,426 (46.1) |
Black | 79,503 (34.4) | 13,314 (33.3) |
Hispanic | 29,028 (12.6) | 5408 (13.5) |
Asian | 6634 (2.9) | 1065 (2.7) |
Other/unknown | 10,095 (4.4) | 1772 (4.4) |
Dialysis vintage, months | ||
mean ± SD | 30.1 ± 39.6 | 44.1 ± 41.2 |
median (p25, p75) | 18 (1, 44) | 34 (14, 62) |
Body mass index, kg/m2 | ||
mean ± SD | 28.1 ± 7.3 | 26.9 ± 7.0 |
median (p25, p75) | 26.7 (22.9, 31.8) | 25.6 (22.1, 30.3) |
Body weight, kg | ||
mean ± SD | 81.3 ± 22.9 | 77.0 ± 21.4 |
median (p25, p75) | 77.6 (65.1, 93.5) | 73.5 (62.1, 88.0) |
Access type, n (%) | ||
Arteriovenous fistula | 53,819 (23.3) | 18,953 (47.4) |
Arteriovenous graft | 21,322 (9.2) | 8302 (20.8) |
Central venous catheter | 37,334 (16.2) | 10,588 (26.5) |
Peritoneal dialysis catheter | 8953 (3.9) | 2122 (5.3) |
Unknown | 109,565 (47.4) | 20 (0.1) |
Etiology end-stage renal disease, n (%) | ||
Diabetes | 97,779 (42.3) | 18,769 (46.9) |
Hypertension | 66,305 (28.7) | 11,341 (28.4) |
Other/unknown | 66,909 (29.0) | 9875 (24.7) |
Diabetes, n (%) | 144,827 (62.7) | 28,507 (71.3) |
Coronary artery disease, n (%) | 11,503 (5.0) | 4118 (10.3) |
Atherosclerosis, n (%) | 7059 (3.1) | 2389 (6.0) |
Atrial fibrillation, n (%) | 110 (0.1) | 27 (0.1) |
Cardiac arrest, n (%) | 218 (0.1) | 88 (0.2) |
Ischemic heart disease, n (%) | 15,340 (6.6) | 5266 (13.2) |
Cerebrovascular disease, n (%) | 1067 (0.5) | 376 (0.9) |
Myocardial infarction, n (%) | 281 (0.1) | 101 (0.3) |
Pericarditis, n (%) | 118 (0.1) | 36 (0.1) |
Cancer (any cause), n (%) | 3010 (1.3) | 1020 (2.6) |
Congestive heart failure, n (%) | 15,954 (6.9) | 5836 (14.6) |
CCI score | ||
mean ± SD | 5.2 ± 1.8 | 5.9 ± 1.9 |
median (p25, p75) | 5 (4, 6) | 6 (5, 7) |
Hemoglobin, g/dL | ||
mean ± SD | 11.6 ± 1.4 | 11.0 ± 1.4 |
median (p25, p75) | 11.6 (10.8, 12.5) | 11.1 (10.1, 11.9) |
Serum albumin, g/dL | ||
mean ± SD | 3.8 ± 0.5 | 3.6 ± 0.5 |
median (p25, p75) | 3.8 (3.5, 4.1) | 3.7 (3.3, 4.0) |
Serum phosphate, mg/dL | ||
mean ± SD | 5.2 ± 1.6 | 5.0 ± 1.7 |
median (p25, p75) | 5.0 (4.1, 5.9) | 4.7 (3.9, 5.8) |
Serum calcium, mg/dL | ||
mean ± SD | 8.8 ± 0.7 | 8.7 ± 0.8 |
median (p25, p75) | 8.8 (8.4, 9.2) | 8.7 (8.2, 9.1) |
Parathyroid hormone, ng/mL | ||
mean ± SD | 380 ± 394 | 361 ± 389 |
median (p25, p75) | 271 (176, 446) | 261 (166, 419) |