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Table 6 Crude and adjusted HRs of mortality, by diet, Charlson index, proteinuria, and GFR (Cox analysis) (LPD-KA and LPD-PFF)

From: Diet as a system: an observational study investigating a multi-choice system of moderately restricted low-protein diets

 

n/N

Crude RR (95% CIs)

p value

Adjusted HR (95% CIs)

p value

Diet

 LPD-KA

37/215

1 (−)

<0.0001

1 (−)

0.5264

 LPD-PFF

59/159

2.16 (1.51–3.08)

 

1.15 (0.75–1.75)

Charlson index

<0.0001

 <7

12/165

1 (−)

<0.0001

1 (−)

 ≥7

84/209

5.53 (3.13–9.77)

 

6.11 (3.28–11.36)

Proteinuria

(g/day)

  

<0.0001

 

0.2107

  < 1

69/207

1 (−)

 

1 (−)

  ≥ 1

27/167

0.49 (0.33–0.72)

 

0.75 (0.48–1.18)

GFR (ml/m)

0.2425

  < 30

78/291

1 (−)

0.3436

1 (−)

  ≥ 30

18/83

0.81 (0.72–1.27)

 

0.74 (0.44–1.23)

  1. GFR-EPI Glomerular filtration rate (EPI formula), RR Relative risk, HR Hazard ratio
  2. statistically significant OR in bold