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Table 4 Incidence of Clinical Endpoints (Cox regression analysis)a

From: Effectiveness of Integrated Care on Delaying Progression of stage 3-4 Chronic Kidney Disease in Rural Communities of Thailand (ESCORT study): a cluster randomized controlled trial

Clinical outcome

Control (n = 208)

Intervention (n = 234)

P-value

Hazard ratio

95%CI

No. of events

Person-years

No. of events

Person-years

All-cause mortality

4

387.8

5

449.6

0.92

1.07

0.29–3.90

CV eventsb

4

384.0

2

448.6

0.33

0.43

0.08–2.34

ESRDc

14

370.5

8

439.6

0.11

0.49

0.21–1.16

50% increase in serum Cr from baseline

31

359.5

23

426.8

0.10

0.64

0.37–1.09

Composite clinical endpointsd

41

344.3

29

417.6

0.03

0.59

0.37–0.96

  1. Data was analyzed by using Cox proportional-hazard model based on intention to treat basis
  2. Abbreviation: CV events cardiovascular events
  3. aIn this analysis, data were censored at the date of death, the date of last visit of patients who loss to follow-up or withdrew from the study
  4. bCV events in this analysis are consisted of acute myocardial infarction and stroke
  5. cEnd-stage renal disease (ESRD) is defined as eGFR < 15 ml/min/1.73 m2
  6. dComposite of clinical endpoints in this study is composed of CV events, ESRD, 50% increase in serum creatinine from baseline