Table 1 Demographic and clinical characteristics of 146 patients with aHUS
From: Turkish pediatric atypical hemolytic uremic syndrome registry: initial analysis of 146 patients
Male (%) / Female (%) | 62 (42.4) / 84 (57.6) |
|---|---|
Current age, years | |
Mean (SD) | 7.98 (5.0) |
Median (IQR) | 6.53 (3.8–11) |
Age at diagnosis, years | |
Mean (SD) | 4.82 (4.4) |
Median (IQR) | 3.5 (1.2–7.4) |
Age category (years) at the time of diagnosis, n (%) | |
<2 | 53 (36.3) |
2 to <5 | 40 (27.4) |
5 to <12 | 38 (26) |
≥12 | 15 (10.3) |
Duration of follow-up (years) | |
Mean (SD) | 2.9 (2.5) |
Median (IQR) | 2.1 (1.2–3.8) |
Consanguinity (%) | 42 (28.8) |
Family history of aHUS (%) | 7 (4.8) |
Anuria (%) /oliguria at admission (%) | 41 (28) / 67 (45.8) |
Duration of anuria at admission (days) | |
Mean (SD) | 6.3 (4.5) |
Median (IQR) | 5 (2–10) |
Duration of oliguria at admission (days) | |
Mean (SD) | 6 (6.8) |
Median (IQR) | 3 (2–7) |
Extrarenal involvement, n (%) | 61 (41.7) |
Central nervous system | 41 (28.1) |
Gastrointestinal system | 16 (10.9) |
Cardiac | 9 (6.1) |
Respiratory system | 10 (6.8) |
Patients with GFR <90 mL/min/1.73 m2 at admission, n (%) | 139 (95.2) |
Hypocomplementemia (%)a | 66 (48.5) |
Renal biopsy at admission (%) | 44 (30.1%) |