Dengue fever in renal transplant patients: a systematic review of literature

BMC Nephrology

Table 5 Summary of immunosuppressive profile, symptoms and signs, laboratory findings, severity of disease, confirmation of diagnosis and outcome, and comparison with general population

	n	%	Prevalence7^a (n = 81,327) %	p
Immunosuppression
Azathioprine	166	51.8
Cyclosporine	166	27.1
MMF	166	43.4
Steroid	166	98.8
Tacrolimus	166	25.9
Symptoms and Signs
Fever at presentation	162	86.4	98.8	0.006
Myalgia	159	47.0	92.4	<0.001
Arthlagia	39	20.2	76.4	<0.001
New bleeding complications	127	14.9	10.2	0.147
Headache	133	34.6	95.8	<0.001
Diarrhea	13	15.3		0.122
Pleural effusions	115	17.4	2.2	<0.001
Ascites	23	34.8	1.1	0.003
Laboratory findings
Thrombocytopenia	127	93.7
Leucopenia	133	66.9
LFT abnormalities	39	71.8
Graft dysfunction	141	58.9
Severity of disease
DHF / DSS	168	16.0	3.7	<0.001
Confirmation of disease
IgM	168	87.5
RT PCR / NS1	168	13.7
Outcome
Alive with a functioning graft	168	84.5
Graft failure	168	6.5
Death	168	8.9	0.062 ^b	<0.001

Abbreviations: LFT liver function tests, RT PCR reverse transcriptase polymerase chain reaction, NS1 non specific antigen 1
^aPrevalence of non-transplant population given by Casali CG et al. [14]
^bFrequency of DHF given in Casali et al. is 3.7%. The mortality of DHF is 3.21% while that of DF is 0.026%. The combined mortality calculated as 0.062%

ISSN: 1471-2369