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Table 5 Risk factors for the prevalence of CVD in C-STRIDE Study (Nov 2011 - Mar 2016)

From: Prevalence and risk factors for cardiovascular disease among chronic kidney disease patients: results from the Chinese cohort study of chronic kidney disease (C-STRIDE)

  Univariate OR (95% CI) P Age and sex adjusted OR (95% CI) P Multivariate adjusted OR (95% CI)a P
Gender
 Male 1.61 (1.25–2.07) <0.001 1.36 (0.96─1.94) 0.09
 Female (ref) 1    1  
Age
 18–44 (ref) 1    1  
 45–64 5.16 (3.56–7.48) <0.001 3.78 (2.55–5.59) <0.001
 65–74 10.25 (6.85–15.34) <0.001 6.07 (3.89–9.47) <0.001
Tobacco use (yes/no) 1.79 (1.41–2.27) <0.001 1.46 (1.071–1.99) 0.017 1.31 (0.95–1.81) 0.10
Exercises < 3.5 h/week (yes/no) 1.07 (0.82–1.41) 0.61 0.81 (0.61–1.07) 0.14 0.80 (0.60–1.08) 0.14
Diabetic (yes/no) 3.08 (2.42–3.93) <0.001 1.93 (1.49–2.49) <.0001 1.70 (1.30–2.23) <0.001
Hypertension (yes/no) 4.53 (2.70–7.58) <0.001 3.37 (2.00–5.68) <.0001 2.57 (1.50–4.41) <0.001
HDL-C <35 mg/dl 1.40 (1.08–1.81) 0.01 1.26 (0.96–1.65) 0.09 1.14 (0.84–1.54) 0.41
LDL-C >120 mg/dl 0.76 (0.58–1.01) 0.05 0.74 (0.56–0.99) 0.04 0.81 (0.59–1.10) 0.17
TG >150 mg/dl 1.06 (0.84–1.35) 0.63 1.09 (0.85–1.40) 0.48 0.98 (0.75–1.28) 0.87
BMI
 <24 (ref) 1   1   1  
 ≥24 1.68 (1.29–2.18) <0.001 1.39 (1.06–1.81) 0.0174 1.30 (0.97–1.72) 0.08
CKD stages
 1–2(ref) 1   1   1  
 3a 4.10 (2.62–6.43) <0.001 2.60 (1.64–4.13) <.0001 2.07 (1.28–3.34) <0.003
 3b 3.83 (2.51–5.85) <0.001 2.22 (1.44–3.44) 0.0003 1.66 (1.00–2.62) 0.03
 4 5.19 (3.47–7.76) <0.001 3.28 (2.16–4.97) <.0001 2.73 (1.72–4.36) <0.001
P >5 mg/dl 1.03 (0.72–1.45) 0.89 1.25 (0.87–1.795) 0.23 0.96 (0.66–1.42) 0.85
Ca <8.4 mg/dl 1 (0.74–1.35) 0.10 0.97 (0.71–1.33) 0.86 0.97 (0.69–1.36) 0.85
IPTH >65 pg/mL 1.62 (1.25–2.09) <0.001 1.42 (1.09–1.85) 0.01 1.03 (0.77–1.40) 0.83
AAC 3.71 (2.58–5.33) <0.001 2.18 (1.498–3.18) <.0001 1.82 (1.23–2.70) 0.003
Hb <11 g/dl 1.06 (0.78–1.43) 0.72 0.93 (0.68–1.27) 0.64 0.67 (0.47–0.95) 0.03
  1. Note: aAll variables listed in the table were included in the multivariate adjusted analysis. OR odds ratio, CI confidence interval, LDL-C low density lipoprotein cholesterol, HDL-C high density lipoprotein cholesterol, TG triglycerides, BMI body mass index, P serum phosphorus, Ca serum calcium, iPTH intact parathyroid hormone, AAC abdominal aorta calcification, Hb hemoglobin