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Table 5 Risk factors for the prevalence of CVD in C-STRIDE Study (Nov 2011 - Mar 2016)

From: Prevalence and risk factors for cardiovascular disease among chronic kidney disease patients: results from the Chinese cohort study of chronic kidney disease (C-STRIDE)

 

Univariate OR (95% CI)

P

Age and sex adjusted OR (95% CI)

P

Multivariate adjusted OR (95% CI)a

P

Gender

 Male

1.61 (1.25–2.07)

<0.001

−

−

1.36 (0.96─1.94)

0.09

 Female (ref)

1

 

−

 

1

 

Age

 18–44 (ref)

1

 

−

 

1

 

 45–64

5.16 (3.56–7.48)

<0.001

−

−

3.78 (2.55–5.59)

<0.001

 65–74

10.25 (6.85–15.34)

<0.001

−

−

6.07 (3.89–9.47)

<0.001

Tobacco use (yes/no)

1.79 (1.41–2.27)

<0.001

1.46 (1.071–1.99)

0.017

1.31 (0.95–1.81)

0.10

Exercises < 3.5 h/week (yes/no)

1.07 (0.82–1.41)

0.61

0.81 (0.61–1.07)

0.14

0.80 (0.60–1.08)

0.14

Diabetic (yes/no)

3.08 (2.42–3.93)

<0.001

1.93 (1.49–2.49)

<.0001

1.70 (1.30–2.23)

<0.001

Hypertension (yes/no)

4.53 (2.70–7.58)

<0.001

3.37 (2.00–5.68)

<.0001

2.57 (1.50–4.41)

<0.001

HDL-C <35 mg/dl

1.40 (1.08–1.81)

0.01

1.26 (0.96–1.65)

0.09

1.14 (0.84–1.54)

0.41

LDL-C >120 mg/dl

0.76 (0.58–1.01)

0.05

0.74 (0.56–0.99)

0.04

0.81 (0.59–1.10)

0.17

TG >150 mg/dl

1.06 (0.84–1.35)

0.63

1.09 (0.85–1.40)

0.48

0.98 (0.75–1.28)

0.87

BMI

 <24 (ref)

1

 

1

 

1

 

 ≥24

1.68 (1.29–2.18)

<0.001

1.39 (1.06–1.81)

0.0174

1.30 (0.97–1.72)

0.08

CKD stages

 1–2(ref)

1

 

1

 

1

 

 3a

4.10 (2.62–6.43)

<0.001

2.60 (1.64–4.13)

<.0001

2.07 (1.28–3.34)

<0.003

 3b

3.83 (2.51–5.85)

<0.001

2.22 (1.44–3.44)

0.0003

1.66 (1.00–2.62)

0.03

 4

5.19 (3.47–7.76)

<0.001

3.28 (2.16–4.97)

<.0001

2.73 (1.72–4.36)

<0.001

P >5 mg/dl

1.03 (0.72–1.45)

0.89

1.25 (0.87–1.795)

0.23

0.96 (0.66–1.42)

0.85

Ca <8.4 mg/dl

1 (0.74–1.35)

0.10

0.97 (0.71–1.33)

0.86

0.97 (0.69–1.36)

0.85

IPTH >65 pg/mL

1.62 (1.25–2.09)

<0.001

1.42 (1.09–1.85)

0.01

1.03 (0.77–1.40)

0.83

AAC

3.71 (2.58–5.33)

<0.001

2.18 (1.498–3.18)

<.0001

1.82 (1.23–2.70)

0.003

Hb <11 g/dl

1.06 (0.78–1.43)

0.72

0.93 (0.68–1.27)

0.64

0.67 (0.47–0.95)

0.03

  1. Note: aAll variables listed in the table were included in the multivariate adjusted analysis. OR odds ratio, CI confidence interval, LDL-C low density lipoprotein cholesterol, HDL-C high density lipoprotein cholesterol, TG triglycerides, BMI body mass index, P serum phosphorus, Ca serum calcium, iPTH intact parathyroid hormone, AAC abdominal aorta calcification, Hb hemoglobin