Awareness and knowledge among internal medicine house-staff for dose adjustment of commonly used medications in patients with CKD

Table 3 Comparisons for total scores of correct ‘medication dose adjustment at appropriate GFR level’ knowledge

Variable	Possible Total Score	PGY1 M (SD)	PGY2 M (SD)	PGY3 M (SD)	ANOVA or Kruskal Wallis p-value	ANCOVA p-value	Post-hoc
Allergy	3	1.2 (0.81)	1.5 (0.71)	1.6 (0.57)	<0.001	0.001	PGY2>PGY1 PGY3>PGY1
Analgesic	4	0.5 (0.69)	0.6 (0.77)	0.7 (0.66)	0.25	–	–
Cardiovascular	7	2.1 (1.06)	2.4 (0.99)	2.5 (0.84)	0.004	0.03	PGY2>PGY1 PGY3>PGY1
Endocrine	3	0.7 (0.76)	0.9 (0.79)	1.1 (0.87)	0.001	0.001	PGY2>PGY1 PGY3>PGY1
Gastrointestinal	2	0.7 (0.55)	0.9 (0.50)	0.9 (0.45)	0.001	0.002	PGY2 > PGY1 PGY3>PGY1
Neuropsychotropic	5	1.4 (0.95)	1.6 (0.95)	1.5 (0.89)	0.34	–	–
Rheumatologic	2	0.4 (0.62)	0.5 (0.73)	0.6 (0.76)	0.054	–	–
Overall medication score	26	6.8 (3.09)	8.3 (2.91)	8.8 (2.02)	<0.001	<0.001	PGY2>PGY1 PGY3>PGY1

Note: M mean, SD standard deviation, PGY post-graduate year, ANOVA analysis of variance, ANCOVA analysis of covariance. Sample sizes slightly vary due to omissions by participants. Endocrine, pain, and rheumatologic had skewed distributions and non-parametric analyses of the Kruskall Wallis test were performed instead of ANOVA. For endocrine, the Mann–Whitney test was performed instead of LSD post-hoc tests and rank ANCOVA (Quade’s test) was performed instead of ANCOVA

ISSN: 1471-2369