Table 1 Data to be collected

Donor and Recipient

Demographic Data

Age

Gender

Ethnicity

Weight

Body mass index

Recipient Details

Comorbidities

Indication for transplant

Perioperative Details

Volume of donor fluid intake—oral and intravenous

Preoperative donor urine output

Intraoperative donor urine output

Donor fluid boluses and response to fluid challenge.

Surgeon performing the operation

Duration of surgery

Cold and warm ischaemic times

Primary and Secondary Outcome

Data

Donor NGAL and BNP (4 measurements): preoperative (day −1), immediately preoperative (day 0), immediately postoperative (day 0), postoperative

(day +1)

Recipient NGAL (3 measurements): preoperative (baseline), immediately post-operative, postoperative

(day +1).

Donor eGFR: days 1–4, week 6 and 1 year

Recipient eGFR: week 6 and 1 year

Recipient delayed graft function (DGF)—defined as use of dialysis in the first week postoperatively

1 year graft and patient survival in recipient

Donor intraoperative haemodynamics (including blood pressure, heart rate, stroke volume index, cardiac index and systemic vascular resistance).

Biomarkers of AKI, including N-GAL, KIM-1 and leukocyte subsets, in blood obtained from renal vein during retrieval and implantation surgery

Donor and recipient perioperative mortality

Donor and recipient perioperative complications

(including cardiorespiratory complications, time to first bowel motion, infective complications, length of hospital stay, readmission)