Table 3 Planimetric, mass, volumetric and hemodynamic parameters of the LV and the parameters of LVH in patients after RT
Parameter | immediately after RT | 3 months after RT | 6 months after RT | 1 year after RT | 3 years after RT | P | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 (n = 42) | 2 (n = 42) | 3 (n = 42) | 4 (n = 42) | 5 (n = 42) | 1vs2 | 1vs3 | 1vs4 | 1vs5 | 2v3 | 3vs5 | 4vs5 | |
LV dimensions | ||||||||||||
LVEDd [mm] | 52.5 (±5.1) | 50.7 (±4.5) | 50.5 (±4.6) | 50.1 (±4.7) | 49.7 (±4.8) | 0.047 | 0.017 | 0.001 | <0.001 | 0.953 | 0.072 | 0.247 |
LVESd [mm] | 35.1 (±5.5) | 34.6 (±3.7) | 34.4 (±4.3) | 33.9 (±4.9) | 32.0 (±4.7) | 0.153 | 0.141 | 0.011 | 0.004 | 0.580 | 0.007 | 0.009 |
PWDd [mm] | 12.4 (±1.4) | 12.2 (±1.6) | 11.9 (±1.3) | 11.8 (±1.7) | 11.2 (±1.2) | 0.91 | 0.01 | 0.233 | <0.001 | 0.684 | 0.001 | 0.072 |
PWSd [mm] | 15.3 (±1.2) | 16.3 (±1.5) | 16.6 (±2.2) | 16.0 (±2.3) | 17.4 (±2.0) | 0.125 | 0.007 | 0.580 | <0.001 | 0.450 | 0.001 | 0.027 |
IVSDd [mm] | 13.4 (±1.4) | 13.3 (±0.9) | 13.0 (±0.9) | 12.1 (±0.8) | 11.8 (±1.3) | 0.366 | 0.363 | 0.003 | <0.001 | 0.142 | 0.01 | 0.03 |
IVSSd [mm] | 16.1 (±1.5) | 16.3 (±1.3) | 17.6 (±2.0) | 16.8 (±2.0) | 17.3 (±1.9) | 0.680 | <0.001 | 0.034 | <0.001 | 0.175 | 0.523 | 0.980 |
LVM indices | ||||||||||||
LVM [g] | 329.5 (±73.4) | 330.1 (±77.2) | 323.0 (±74.9) | 309.9 (±74.9) | 283.9 (±62.0) | 0.857 | 0.254 | 0.008 | <0.001 | 0.189 | <0.001 | 0.007 |
LVMI [g/m2] | 173.9 (±38.6) | 173.4 (±34.9) | 171.2 (±35.6) | 165.3 (±34.2) | 149.3 (±33.0) | 0.784 | 0.243 | 0.011 | <0.001 | 0.124 | <0.001 | 0.004 |
LV volumetric parameters | ||||||||||||
LVEDV [ml] | 134.5 (±29.2) | 124.2 (±31.3) | 123.3 (±28.9) | 122.2 (±34.5) | 118.5 (±25.7) | 0.012 | 0.009 | 0.002 | 0.001 | 0.834 | 0.052 | 0.274 |
LVESV [m] | 53.25 (±19.90) | 50.13 (±13.56) | 50.43 (±15.61) | 48.56 (±18.52) | 42.35 (±15.34) | 0.146 | 0.118 | 0.021 | 0.005 | 0.439 | 0.008 | 0.011 |
SV [ml] | 81.31 (±19.36) | 78.9 (±15.60) | 77.8 (±17.62) | 76.5 (±21.1) | 76.23 (±18.05) | 0.033 | 0.028 | 0.023 | 0.013 | 0.486 | 0.754 | 0.765 |
Cardiac output parameters | ||||||||||||
CO [l/min] | 6.16 (±0.76) | 5.81 (±0.59) | 5.77 (±0.71) | 5.54 (±0.82) | 5.55 (±0.68) | 0.019 | 0.014 | 0.011 | 0.007 | 0.685 | 0.232 | 0.983 |
CI [l/min/m2] | 3.29 (±0.49) | 3.10 (±0.47) | 3.09 (±0.51) | 2.97 (±0.45) | 2.98 (±0.51) | 0.021 | 0.017 | 0.013 | 0.009 | 0.832 | 0.274 | 0.934 |
Contractility parameters | ||||||||||||
EF [%] | 60.98 (±9.93) | 59.25 (±8.92) | 60.54 (±9.34) | 61.03 (±10.11) | 64.59 (±9.11) | 0.865 | 0.659 | 0.184 | 0.008 | 0.236 | 0.009 | 0.018 |
FS [%] | 33.36 (±7.01) | 32.67 (±6.72) | 33.02 (±7.34) | 33.78 (±9.32) | 35.83 (±6.58) | 0.753 | 0.769 | 0.238 | 0.011 | 0.327 | 0.012 | 0.045 |