Table 3 Variables independently associated with (A) plasma TF, (B) plasma suPAR, (C) endothelial dysfunctions markers, (D) Cu/Zn SOD, and neopterin levels in patients with CKD
Independent variable | Regression coefficient | P value | ||
|---|---|---|---|---|
A | TF | TM | 0.489 | 0.007 |
Multiple R for variables in the model– 0.490, multiple R2 – 0.239, adjusted R2 – 0.211, p < 0.007 | ||||
B | suPAR | uPA | 0.418 | <0.0001 |
hs-CRP | 0.373 | 0.0002 | ||
neopterin | 0.500 | 0.0012 | ||
lymphocytes | −0.249 | 0.0046 | ||
TM | 0.307 | 0.0084 | ||
sICAM-1 | 0.230 | 0.0171 | ||
vWF | 0.157 | 0.0244 | ||
Cu/Zn SOD | 0.156 | 0.0482 | ||
Multiple R for variables in the model – 0.985, multiple R2 – 0.971, adjusted R2 – 0.934, p < 0.0001 | ||||
C | vWF | age | 0.371 | 0.0104 |
F1 + 2 | −0.276 | 0.0324 | ||
TM* | PAP | 0.497 | 0.0003 | |
IS | 0.426 | 0.0008 | ||
suPAR | 0.399 | 0.0024 | ||
sVCAM-1^ | IS | 0.562 | 0.0007 | |
sICAM-1 | 0.557 | 0.0008 | ||
neopterin | 0.359 | 0.0140 | ||
sICAM-1# | sVCAM-1 | 0.547 | <0.0001 | |
suPAR | 0.357 | 0.0101 | ||
Multiple R for variables in the model – 0.633 (*0.863; ^0.960; #0.785), multiple R2 – 0.400 (*0.745; ^0.922; #0.617), adjusted R2 – 0.349 (*0.713; ^0.873; #0.574), all p < 0.0001 | ||||
D | Cu/Zn SOD | IS | 0.411 | 0.0031 |
TFPI | 0.405 | 0.0071 | ||
sICAM-1 | 0.366 | 0.0093 | ||
F1 + 2 | 0.250 | 0.0442 | ||
neopterin* | sVCAM-1 | 0.659 | 0.0010 | |
TM | 0.598 | 0.0062 | ||
TF | 0.496 | 0.0100 | ||
IS | 0.456 | 0.0119 | ||
Hemoglobin | −0.324 | 0.0471 | ||
Multiple R for variables in the model – 0.655 (*0.926), multiple R2 – 0.429 (*0.857), adjusted R2 – 0.336 (*0.786), both p < 0.0001 | ||||