Overall (n = 15) | Initial therapy (n = 7) | Second-line therapy (n = 8) | |||||||
---|---|---|---|---|---|---|---|---|---|
Variable | Baseline | 1-Year | P value | Baseline | 1-Year | P value | Baseline | 1-Year | P value |
UPCR (g/g) | 8.2 (6.6–11.1) | 0.3 (0.2–0.7) | <0.001 | 6.9 (5.2–10.2) | 0.2 (0.1–0.5) | 0.02 | 10.1 (8–11.7) | 0.6 (0.3–0.7) | 0.01 |
Creatinine (mg/dL) | 1.2 (0.8–1.5) | 1.0 (0.8–1.2) | 0.44 | 0.8 (0.5–0.9) | 0.8 (0.7–1.0) | 0.13 | 1.3 (1.2–2.1) | 1.2 (1.1–1.7) | 0.02 |
Albumin (mg/dL) | 2.7 (2.5–2.8) | 4.2 (4–4.4) | <0.001 | 2.7 (2.5–2.8) | 4.2 (3.9–4.4) | 0.02 | 2.6 (2.4–3.1) | 4.2 (4.0–4.4) | 0.01 |
Cholesterol (mg/dL)a | 350 (252–371) | 189 (148–220) | 0.001 | 341 (252–367) | 167 (128–191) | 0.02 | 371 (249–438) | 207 (155–251) | 0.02 |
Triglycerides (mg/dL) | 172 (122–270) | 189 (148–220) | 0.40 | 134 (77–192) | 105 (80–244) | 0.74 | 177 (155–546) | 182 (152–204) | 0.24 |
IgG (mg/dL)b | 314 (199–551) | 730 (538–908) | 0.003 | 499 (296–731) | 806 (676–1027) | 0.02 | 199 (198–308) | 611 (364–676) | 0.08 |