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Table 5 Cox proportional hazard univariate and multivariate analyses: risk factors vs. peritonitis and technique failure

From: Peritonitis outcomes in patients with HIV and end-stage renal failure on peritoneal dialysis: a prospective cohort study

 

Univariate Cox proportional hazards

Multivariable Cox proportional hazards

Variable

Hazard ratio

(95% Conf. Interval)

P value

Hazard ratio

(95% Conf. Interval)

P value

Peritonitisd

 HIV

2.41 (1.69–3.45)

<0.001

1.84 (1.07–3.16)

0.027

 Race

0.19 (0.06–0.57

0.003

0.54 (0.05–5.66)

0.607

 Catheter insertion methoda

1.86 (1.28–2.71)

0.001

0.63 (0.28–1.42)

0.269

 Catheter insertion siteb

2.20 (1.45–3.33

<0.001

2.17 (0.84–5.58)

0.108

 Diabetes

2.22 (1.35–3.66)

0.002

2.09 (1.09–4.03)

0.027

 BMI

1.04 (1.00–1.08

0.033

1.01 (0.95–1.09)

0.720

 Waist circumference

1.02 (1.00–1.04)

0.017

1.03 (0.99–1.06)

0.151

 Baseline hemoglobin

0.85 (0.77–0.94)

0.002

1.02 (0.88–1.19)

0.786

 Baseline albumin

0.95 (0.93–0.98)

0.001

0.98 (0.94–1.02)

0.298

 Baseline CRP

1.00 (1.00–1.01)

0.004

1.00 (1.00–1.00)

0.652

 Baseline CD4 count (cells/µL)

  HIV-negative

Reference

  

  CD4 < 200

4.54 (2.35–8.76)

<0.001

3.28 (1.42–7.61)

0.006

  CD4 200–350

2.61 (1.6–4.24)

<0.001

1.18 (0.66–2.12)

0.577

  CD4 ≥ 350

2.10 (1.39–3.15)

<0.001

1.00

 

 Residence

  City

Reference

  

  Townshipc

5.94 (2.17–16.25)

0.001

5.56 (0.82–37.50)

0.078

  Rural area

6.07 (2.19–16.8)

0.001

4.68 (0.70–31.07)

0.110

Technique failuree

  HIV

1.42 (0.73–2.73)

0.299

0.39 (0.14–1.11)

0.077

  Peritonitis

9.29 (2.84–30.36)

<0.001

14.47 (2.79–75.00)

0.001

  Catheter insertion site

2.33 (1.09–4.97)

0.029

2.73 (0.49–15.21)

0.252

  Catheter insertion method

1.62 (0.79–3.30)

0.185

0.69 (0.13–3.71)

0.663

  Average hemoglobin

0.72 (0.59–0.88)

0.001

0.75 (0.59–0.95)

0.016

  Average CRP

1.02 (1.01–1.02)

<0.001

1.02 (1.01–1.03)

<0.001

  1. BMI Body mass index, CD cluster of differentiation, CRP C-reactive protein, HIV human immunodeficiency virus
  2. aCatheter insertion method- laparoscopic vs. percutaneous, bCatheter insertion site - Inkosi Albert Luthuli Central Hospital vs King Edward VIII Hospital, cSouth African Township refers to underdeveloped urban areas created under apartheid for non-white residents
  3. dAdjusted for age, race, gender, smoking, diabetes, body mass index, waist circumference, baseline hemoglobin, baseline serum albumin, baseline C-reactive protein, primary residence, highest education level, employment, baseline CD4 count, Tenckhoff catheter insertion site, and Tenckhoff catheter insertion method (laparoscopic vs. percutaneous)
  4. eAdjusted for HIV, peritonitis, age, gender, smoking, diabetes, body mass index, waist circumference, average hemoglobin, average C-reactive protein, average serum ferritin, primary residence, highest education level, employment, Tenckhoff catheter insertion site, and Tenckhoff catheter insertion method (laparoscopic vs. percutaneous)
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BMC Nephrology

ISSN: 1471-2369

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