Ultrafiltration rate is an important determinant of microcirculatory alterations during chronic renal replacement therapy

Table 1 Baseline characteristics phase I and II

Variables	All (n = 28)	LT (n = 19)	NL (n = 9)	p-value
Men, %	57	42	89	0.04
Age, years	64 [53–74]	60 [49–70]	69 [55–78]	0.29
Years on HD	3 [1–6]	3 [1–7]	3 [1–5]	0.94
Remaining diuresis, l/24 h	0.2 [0–0.5]	0.3 [0–0.6]	0.2 [0–0.4]	0.60
Weight, kg	78 [67–87]	73 [66–79]	85 [88–92]	0.03
BMI, kg/m2	26 [24–28]	27 [23–30]	26 [25–28]	0.94
UF volume, l	2.3 [1.3–3.2]	2.6 [1.6–3.3]	1.7 [1.2–2.1]	0.10
Cause of ESRD, %
Diabetes	32	21	56
Hypertension	18	26	0
ADPKD	7	5	11	0.27
ATN	14	16	11
Miscellaneous	29	32	22
Drugs, %
ß-blocker	61	42	67	1.0
ACE inhibitor	61	74	33	0.1
Calcium antagonist	47	58	22	0.09

LT Lithuania, NL Netherlands, HD hemodialysis, BMI body mass index, UF ultrafiltration, ESRD end stage renal disease, ADKPD autosomal dominant polycystic kidney disease, ATN acute tubular necrosis, ACE angiotensin converting enzyme

ISSN: 1471-2369