Ultrafiltration rate is an important determinant of microcirculatory alterations during chronic renal replacement therapy

Table 2 Results phase I (n = 28). Hemodynamic and microcirculatory variables of small vessels (<20 μm) before and after hemodialysis in combination with linear ultrafiltration

Variables	Baseline	Post HD/UF	p-value
Mean arterial pressure, mmHg	93 [76–111]	96 [84–110]	0.39
Heartrate, beats/min	69 [62–80]	73 [60–84]	0.24
SpO₂, %	97 [96–98]	98 [98–99]	0.009
MFI, AU	3 [2.8–3]	3 [2.8–3]	0.55
TVD, mm/mm²	22.2 [18–29.8]	22.7 [19.9–29]	0.11
PPV, %	98 [96–100]	98 [96–99]	0.35

HD hemodialysis, UF ultrafiltration, SpO ₂ peripheral oxygen saturation, MFI microvascular flow index, AU arbitrary units, TVD total vessel density, PVD perfused vessel density, PPV percentage of perfused vessel

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