Table 3 Results phase II (n = 9). Laboratory data, microcirculatory variables of small vessels (<20 μm) and bioelectrical impedance analysis before and after intervention

 UF

-

1.7 [1.2–2]

 UF rate, l/h

-

1.7 [1.2–2]^†

 MFI, AU

2.8 [2.5–2.9]

2.5 [2.2–2.8]

0.03

 TVD, mm/mm²

17.7 [16.5–18.4]

18.7 [16.1–20.3]

0.26

 Hematocrit, %

37 [35–39]

39 [36–44]

0.11

 NT-pro-BNP, pmol/l

599 [215–1702]

580 [158–1440]

0.01

 Troponine T, ng/l

90 [60–150]

87 [56–130]

0.08

 BCM overhydration, l

1.4 [0.6–3.2]

0.3 [−0.1–0.8]

0.02

 UF

–

0 [0–0]

 UF rate, l/h

–

0 [0–0]^†

 MFI, AU

2.8 [2.5–2.9]

2.8 [2.7–2.9]

0.61

 TVD, mm/mm²

17.7 [16.5–18.4]

18.6 [14.6–19.7]

0.86

 Hematocrit, %

37 [35–39]

NA

 NT-pro-BNP, pmol/l

599 [215–1702]

NA

 Troponine T, ng/l

90 [60–150]

NA

 BCM overhydration, l

1.4 [0.6–3.2]

NA

 UF

1.7 [1.2–2.1]

 UF rate, l/h

0.42 [0.3–5.1]^†

 MFI, AU

2.9 [2.5–3]

2.6 [2.2–2.9]

0.12

 TVD, mm/mm²

17.8 [16.6–18.8]

19.8 [17.9–21.5]

0.07

 Hematocrit, %

38 [35–40]

40 [35–41]

0.18

 T-pro-BNP, pmol/l

618 [279–1926]

536 [167–1003]

0.01

 Troponine T, ng/l

94 [61–179]

84 [62–139]

0.02

 BCM overhydration, l

1.8 [0.5–5.3]

0.3 [−0.9–3.2]

0.02

 UF

2.0 [1.5–2.1]

 UF rate, l/h

0.5 [0.39–0.52]^†

 MFI, AU

2.8 [2.5–3]

2.8 [1.9–2.9]

0.06

 TVD, mm/mm²

18.8 [16.8–20.6]

18.2 [16.9–20.6]

0.77

 Hematocrit, %

37 [34–39]

39 [35–42]

0.12

 NT-pro-BNP, pmol/l

574 [229–2011]

511 [172–1163]

0.01

 Troponine T, ng/l

81 [54–379]

79 [54–387]

0.12

 BCM overhydration, l

2.4 [1.5–5.1]

0.2 [−0.9–4.2]

0.04