|
Genotype/allele
|
AKI patients, n(%)
|
Controls, n(%)
|
Odds ratio (95% CI)
|
P value
|
AKI patients
|
Odds ratio (95% CI)
|
P value
|
|---|
|
Dead, n(%)
|
Alive, n(%)
|
|---|
|
Met11Thr
|
|
Met/Met
|
42 (26.4)
|
51 (42.5)
|
0.486 (0.293–0.805)
|
0.007**
|
9 (18.4)
|
43 (39.1)
|
0.351 (0.155–0.795)
|
0.011
|
|
Met/Thr
|
67 (42.1)
|
54 (45.0)
| | |
20 (40.8)
|
47 (42.7)
| | |
|
Thr/Thr
|
50 (31.5)
|
15 (12.5)
|
3.211 (1.699–6.067)
|
0.001**
|
20 (40.8)
|
20 (18.2)
|
3.103 (1.468–6.557)
|
0.005**
|
|
Allele
|
|
Met
|
151 (47.5)
|
156 (65.0)
|
0.487 (0.345–0.687)
| |
38 (38.8)
|
133 (60.5)
|
0.414 (0.254–0.675)
| |
|
Thr
|
167 (52.5)
|
84 (35.0)
|
2.054 (1.455–2.899)
|
0.001**
|
60 (61.2)
|
87 (39.5)
|
2.414 (1.482–3.933)
|
0.0004**
|
|
Ala160Thr
|
|
Ala/Ala
|
70 (44.0)
|
50 (41.7)
|
1.101 (0.682–1.778)
|
0.715
|
7 (14.3)
|
15 (13.6)
|
1.056 (0.401–2.779)
|
0.913
|
|
Ala/Thr
|
70 (44.0)
|
50 (41.7)
| | |
24 (49.0)
|
50 (45.5)
| | |
|
Thr/Thr
|
19 (12.0)
|
20 (16.6)
|
0.679 (0.344–1.337)
|
0.297
|
18 (36.7)
|
45 (40.9)
|
0.839 (0.419–1.679)
|
0.619
|
|
Allele
|
|
Ala
|
210 (66.0)
|
150 (62.5)
|
1.167 (0.823–1.655)
| |
38 (38.8)
|
80 (36.4)
|
1.108 (0.679–1.810)
| |
|
Thr
|
108 (34.0)
|
90 (37.5)
|
0.857 (0.604–1.216)
|
0.422
|
60 (61.2)
|
140 (63.6)
|
0.902 (0.552–1.474)
|
0.707
|
-
CI confidence interval
- **P values less than 0.01
