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Table 3 Patient characteristics and outcome of patients grouped by the definition used to classify AKI by serum creatinine criteria

From: Incidence, timing and outcome of AKI in critically ill patients varies with the definition used and the addition of urine output criteria

Characteristic of patients

Group 1 No AKI

N = 1078

Group 2 RIFLE, AKIN & KDIGO AKI

N = 212

Group 3 AKIN & KDIGO AKI

N = 70

Group 4 AKIN AKI

N = 14

p value

Age (years; mean (sd))

63 (19)

67 (20)

68 (15)

54 (28)

<0.05 (*)

Male sex (N (%))

681 (63.1)

122 (57.5)

52 (74.3)

8 (57.1)

0.078

Body Mass Index (kg/m2; mean (sd))

25.8 (5.6)

26.2 (5.6)

26 (6.2)

25.6 (4.7)

0.013 (****)

APACHE IV score (mean (sd))

43 (25)

76 (30)

56 (26.5)

51.5 (36.5)

0.001 (***)

Admission type

 • Medical (N (%))

308 (28.6)

114 (53.8)

26 (37.1)

12 (85.7)

0.001

 • Surgical

    

  ◦ Scheduled (N (%))

640 (59.4)

53 (25)

32 (45.7)

2 (14.3)

  ◦ Emergency (N (%))

129 (12)

45 (21.2)

12 (17.1)

0 (0)

Co morbidity

 • diabetes mellitus (N (%))

149 (13.8)

62 (29.2)

9 (12.9)

1 (7.1)

0.001

 • chronic kidney disease (N (%))

5 (0.5)

48 (22.6)

4 (5.7)

0 (0)

0.001

 • chronic dialysis (N (%))

0 (0)

23 (10.8)

1 (1.4)

0 (0)

0.001

ICU Length of stay (days; median [IQR])

2 (2–3)

4 (2–8)

2 (2–4)

13 (4–13)

0.001 (****)

ICU mortality (N (%))

37 (3.4)

30 (14.1)

7 (10)

3 (21.4)

0.001

Hospital mortality (N (%))

64 (5.9)

51 (24.1)

11 (15.7)

3 (21.4)

0.001

  1. Group 1: patients without AKI
  2. Group 2: patients with AKI according to RIFLE, AKIN and KDIGO criteria
  3. Group 3: patients with AKI according to AKIN and KDIGO
  4. Group 4: patients with AKI according to AKIN
  5. IQR interquartile range
  6. N number of patients
  7. APACHE IV Acute Physiology and Chronic Health Evaluation IV
  8. ICU intensive care unit
  9. LoS length of stay
  10. (*) group 1 vs group 2 and 3, group 2 vs group 1 and 4, group 3 vs group 1 and 4
  11. (***) group 2 vs group 1, 3 en 4, group 3 vs group 1 & 2
  12. (****) group 1 vs group 2 and 4, group 3 vs group 1 and 2, group 4 vs group 1, 2 and 3