Table 5 Stage II variables used for multivariable analyses

Chen et al [29]

Urine TGF- β

Unilateral ureteral obstruction requiring percutaneous nephrostomy

NA

Harris et al [30]

Blood TGF- β

Renal transplant recipients

Acute cellular rejection

Wong et al [31]

Blood total and active TGF- β 1

Type II diabetes

Sex, age, baseline eGFR, randomized treatment interventions^a, urinary albumin/creatinine ratio, hemoglobin A1c, BMI, diabetes duration, and history of macrovascular or microvascular disease

Hsu et al [27]

Blood MMP-2

Non diabetic patients referred for coronary angiography

Age, sex, smoking status, BMI, systolic blood pressure, fasting glucose, total cholesterol, and baseline eGFR

Shi et al [28]

Urine MMP-2

Chronic tubulointerstitial nephropathy

Age, baseline eGFR, mean blood pressure

Titan et al [32]

Urine MCP-1

Macroalbuminuric type II diabetes

Baseline creatinine clearance, baseline 24 h proteinuria, and systolic blood pressure

Verhave et al [33]

Urine MCP-1

Diabetic nephropathy

Proteinuria, TGF-B

Ogliari et al [34]

Blood MCP-1

SPK recipients

Hemoglobin A1c, years of dialysis pre transplant, recipient BMI, enteric drainage, >1 episode of rejection, type of immunosuppression

Nadkarni et al [35]

Urine MCP-1

Type II diabetes

Hemoglobin A1c, mean arterial pressure, history of cardiovascular disease, intensive glycemic and blood pressure control, fibrates, angiotensin receptor blockers, angiotensin converting enzyme inhibitors, thiazolidinedione, baseline eGFR, urinary albumin-creatinine ratio.