Table 1 Study population characteristics at baseline and follow-up. The RENIS-FU study

Male gender, n (%)

781 (49%)

643 (49%)

Age, years

58.1 (3.8)

63.6 (4.0)

Body mass index, kg/m2

27.2 (4.0)

27.1 (4.0)

0.59

Hypertension^b, n (%)

674 (42%)

672 (52%)

<0.001

Systolic BP, mmHg

129.4 (17.5)

130.5 (16.9)

0.001

Diastolic BP, mmHg

83.4 (9.8)

81.9 (9.3)

<0.001

Pulse pressure, mmHg

46.1 (11.4)

48.6 (12.2)

<0.001

Mean arterial BP, mmHg

98.7 (11.7)

98.1 (10.9)

0.08

Pulse frequency, beats/min

66.6 (9.8)

64.5 (9.2)

<0.001

Antihypertensive medication, n (%)

289 (18%)

405 (31%)

<0.001

 ACE inhibitor, n (%)

28 (1.8%)

48 (3.7%)

<0.001

 A2 blocker, n (%)

132 (8.3%)

201 (15.5%)

<0.001

 Betablocker, n (%)

67 (4.2%)

93 (7.2%)

<0.001

 Calcium blocker, n (%)

80 (5.0%)

126 (9.7%)

<0.001

 Diuretic, n (%)

140 (8.8%)

203 (15.6%)

<0.001

 Other antihypertenives, n (%)

1 (0.1%)

5 (0.4%)

0.06

Current smoker, n (%)

322 (20%)

173 (13%)

<0.001

Use of alcohol more than 2–4 times a month, n (%)

434 (27%)

431 (33%)

0.01

LDL cholesterol, mmol/L

3.67 (0.86)

3.58 (0.90)

<0.001

HDL cholesterol, mmol/L

1.54 (0.42)

1.63 (0.46)

<0.001

Fasting triglycerides, mmol/L

1.00 (0.80 to 1.50)

1.00 (0.80 to 1.30)

0.12

Fasting glucose, mmol/L

5.30 (5.00 to 5.60)

5.40 (5.10 to 5.80)

<0.001

Urinary albumin-creatinine ratio, mg/mmol

0.23 (0.10 to 0.54)

0.34 (0.10 to 0.58)

<0.001

Absolute GFR, mL/min

103.8 (19.9)

98.2 (19.8)

<0.001

GFR, mL/min/1.73 m2

93.8 (14.3)

88.9 (14.5)

<0.001