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Table 1 Study population characteristics at baseline and follow-up. The RENIS-FU study

From: Blood pressure and age-related GFR decline in the general population

  Baseline Follow-up P-value for differencea
N (%) 1594 1299  
Male gender, n (%) 781 (49%) 643 (49%)  
Age, years 58.1 (3.8) 63.6 (4.0)  
Body mass index, kg/m2 27.2 (4.0) 27.1 (4.0) 0.59
Hypertensionb, n (%) 674 (42%) 672 (52%) <0.001
Systolic BP, mmHg 129.4 (17.5) 130.5 (16.9) 0.001
Diastolic BP, mmHg 83.4 (9.8) 81.9 (9.3) <0.001
Pulse pressure, mmHg 46.1 (11.4) 48.6 (12.2) <0.001
Mean arterial BP, mmHg 98.7 (11.7) 98.1 (10.9) 0.08
Pulse frequency, beats/min 66.6 (9.8) 64.5 (9.2) <0.001
Antihypertensive medication, n (%) 289 (18%) 405 (31%) <0.001
 ACE inhibitor, n (%) 28 (1.8%) 48 (3.7%) <0.001
 A2 blocker, n (%) 132 (8.3%) 201 (15.5%) <0.001
 Betablocker, n (%) 67 (4.2%) 93 (7.2%) <0.001
 Calcium blocker, n (%) 80 (5.0%) 126 (9.7%) <0.001
 Diuretic, n (%) 140 (8.8%) 203 (15.6%) <0.001
 Other antihypertenives, n (%) 1 (0.1%) 5 (0.4%) 0.06
Current smoker, n (%) 322 (20%) 173 (13%) <0.001
Use of alcohol more than 2–4 times a month, n (%) 434 (27%) 431 (33%) 0.01
LDL cholesterol, mmol/L 3.67 (0.86) 3.58 (0.90) <0.001
HDL cholesterol, mmol/L 1.54 (0.42) 1.63 (0.46) <0.001
Fasting triglycerides, mmol/L 1.00 (0.80 to 1.50) 1.00 (0.80 to 1.30) 0.12
Fasting glucose, mmol/L 5.30 (5.00 to 5.60) 5.40 (5.10 to 5.80) <0.001
Urinary albumin-creatinine ratio, mg/mmol 0.23 (0.10 to 0.54) 0.34 (0.10 to 0.58) <0.001
Absolute GFR, mL/min 103.8 (19.9) 98.2 (19.8) <0.001
GFR, mL/min/1.73 m2 93.8 (14.3) 88.9 (14.5) <0.001
  1. Estimates are given as mean (standard deviation), median (interquartile range) or percent
  2. Abbreviations: RENIS-FU Study the Renal Iohexol-clearance Survey Follow-up Study, HDL high-density lipoprotein, LDL low-density lipoprotein, BP blood pressure, GFR glomerular filtration rate
  3. aPaired statistical tests for those who participated both at baseline and follow-up
  4. bSystolic BP > = 140, diastolic BP > = 90 or antihypertensive medication