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Table 1 Histopathology (haematoxylin-eosin) scoring of explanted kidneys for mononuclear inflammatory cell infiltration from four groups at 400x magnification where the groups have been scored: 0 = no damage, 1 = mild, 2 = moderate, 3 = severe and 4 = very severe/extensive

From: Ascorbic acid ameliorates renal injury in a murine model of contrast-induced nephropathy

Test group

Individual replicate mouse kidney

1

2

3

Group 1 – Low dose AA

1+ cortex

0 medulla

1+ cortex

medulla not present

1+ cortex

medulla traumatised

Group 2 – High dose AA

1+ cortex

0 medulla

2+ cortex

0 medulla

1+ cortex

medulla not present

Group 3 – Positive Control

3+ cortex

0 medulla

3+ cortex

very little medulla present

3+ cortex and neutrophils

1+ medulla and neutrophils

Group 4 – Negative Control

2+ cortex

1+ medulla

2+ cortex

2+ medulla

2+ cortex

1+ medulla