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Table 1 Histopathology (haematoxylin-eosin) scoring of explanted kidneys for mononuclear inflammatory cell infiltration from four groups at 400x magnification where the groups have been scored: 0 = no damage, 1 = mild, 2 = moderate, 3 = severe and 4 = very severe/extensive

From: Ascorbic acid ameliorates renal injury in a murine model of contrast-induced nephropathy

Test group Individual replicate mouse kidney
1 2 3
Group 1 – Low dose AA 1+ cortex
0 medulla
1+ cortex
medulla not present
1+ cortex
medulla traumatised
Group 2 – High dose AA 1+ cortex
0 medulla
2+ cortex
0 medulla
1+ cortex
medulla not present
Group 3 – Positive Control 3+ cortex
0 medulla
3+ cortex
very little medulla present
3+ cortex and neutrophils
1+ medulla and neutrophils
Group 4 – Negative Control 2+ cortex
1+ medulla
2+ cortex
2+ medulla
2+ cortex
1+ medulla