From: Renal effects of metallothionein induction by zinc in vitro and in vivo
 | Median MTT expression (95% CI) | |||||
---|---|---|---|---|---|---|
Zinc concentration | Control | 5 μg/ml (17.4 μM) | 10 μg/ml (34.8 μM) | 15 μg/ml (52.2 μM) | p-value | |
Environment | Normal I | 1.90 (1.49–2.43) | 5.22 (4.09–6.66) | 11.56 (9.06–14.76) | 34.94 (26.85–45.47) | 0.089 |
Hypoxia III | 1.53 (1.20–1.95) | 4.18 (3.28–5.34) | 9.27 (7.26–11.83) | 28.00 (21.52–36.44) | ||
Normal II | 0.59 (0.46–0.75) | 1.62 (1.27–2.05) | 3.58 (2.82–4.55) | 10.81 (8.44–13.85) | 0.23 | |
Hypoxia IV | 0.50 (0.39–0.63) | 1.37 (1.08–1.74) | 3.03 (2.38–3.85) | 9.15 (7.15–11.72) | ||
Normal II | 0.59 (0.46–0.75) | 1.62 (1.27–2.05) | 3.58 (2.82–4.55) | 10.81 (8.44–13.85) | 0.25 | |
Hypoxia V | 0.51 (0.40–0.65) | 1.39 (1.09–1.78) | 3.08 (2.42–3.93) | 9.32 (7.16–12.12) |