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Table 2 Linear regression analysis of the association between plasma TGF-β (per doubling) and eGFR and ACR

From: Higher plasma transforming growth factor (TGF)-β is associated with kidney disease in older community dwelling adults

Model

eGFR

Urinary ACR

β (95% C.I.)

p-value

β (95% C.I.)

p-value

M0

–1.54

(–2.44,–0.63)

<0.001

0.09

(0,0.18)

0.055

M1

–1.41

(–2.27,–0.55)

<0.001

0.06

(–0.03,0.15)

0.19

M2

–1.18

(–2.03,–0.32)

0.007

0.04

(–0.05,013)

0.35

  1. M0: unadjusted analysis
  2. M1: M0 + age, male gender, and black race
  3. M2: M1 + current smoking status, hypertension, diabetes mellitus, body mass index, LDL-cholesterol, triglycerides, history of cardiovascular disease, and C-reactive protein