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Table 4 Logistic regression analysis of parameters associated with acute kidney injury, Yangon, Myanmar, 2015–2016

From: Clinical and laboratory parameters associated with acute kidney injury in patients with snakebite envenomation: a prospective observational study from Myanmar

Characteristic

Univariate analysis

Multivariate analysis

n

OR (95% CI)

p value

n

OR (95% CI)

p value

Clinical parameters

      

Bites from Viperidae or presenting clinical syndrome of Viperidae

258

  

244

  

 Yes

 

17.44 (6.01–50.57)

<0.001

 

9.65 (2.42–38.44)

0.001

 No

 

1.00 (Reference)

  

1.00 (Reference)

 

Local swelling

258

     

 Grades II–IV

 

4.24 (2.45–7.31)

<0.001

   

 Grades 0-I

 

1.00 (Reference)

    

Hypotension

258

     

 Yes

 

9.08 (4.26–19.38)

<0.001

   

 No

 

1.00 (Reference)

    

Laboratory parameters

      

WBC (cells/μL)

258

  

244

  

  > 10 × 103

 

6.62 (3.41–12.83)

<0.001

 

3.55 (1.35–9.34)

0.010

  ≤ 10 × 103

 

1.00 (Reference)

  

1.00 (Reference)

 

Overt DIC

258

  

244

  

 Yes

 

4.68 (2.76–7.95)

<0.001

 

2.23 (1.02–4.89)

0.045

 No

 

1.00 (Reference)

  

1.00 (Reference)

 

Capillary leakage

258

     

 Yes

 

6.16 (2.31–16.46)

<0.001

   

 No

 

1.00 (Reference)

    

Creatine kinase (IU/L)

256

  

244

  

  > 500

 

10.14 (5.46–18.83)

<0.001

 

4.06 (1.71–9.63)

0.001

  ≤ 500

 

1.00 (Reference)

  

1.00 (Reference)

 

Blood sugar (mg/dL)

258

     

  ≥ 150

 

2.29 (2.00–4.37)

0.012

   

  < 150

 

1.00 (Reference)

    

Serum sodium (mmol/L)

258

  

244

  

  < 135 mmol/L

 

7.27 (4.13–12.82)

<0.001

 

4.37 (2.04–9.38)

<0.001

  ≥ 135 mmol/L

 

1.00 (Reference)

  

1.00 (Reference)

 

Microscopic hematuria

255

  

244

  

 Yes

 

10.16 (5.02–20.57)

<0.001

 

3.60 (1.45–8.91)

0.006

 No

 

1.00 (Reference)

  

1.00 (Reference)

 

Management

      

Site of management

258

     

 Ward

 

5.15 (2.48–10.68)

<0.001

   

 ICU

 

1.00 (Reference)

    

Time from bite to receiving antivenom (hours)

250

  

244

  

  ≥ 2

 

2.20 (1.27–3.80)

0.005

 

3.73 (1.48–9.37)

0.005

  < 2

 

1.00 (Reference)

  

1.00 (Reference)

 
  1. Abbreviations: CI confidence interval, DIC disseminated intravascular coagulation, ICU intensive care unit, OR odds ratio, WBC white blood cell