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Table 6 Univariate and multivariate analysis of clinical and laboratory parameters of adults bitten by Viperidae or presenting the clinical syndrome of Viperidae for identifying acute kidney injury at presentation

From: Clinical and laboratory parameters associated with acute kidney injury in patients with snakebite envenomation: a prospective observational study from Myanmar

Characteristic

Univariate analysis

Multivariate analysis

n

OR (95% CI)

p value

n

OR (95% CI)

p value

Hypotension

164

  

153

  

 Yes

 

8.42 (3.47–20.39)

<0.001

 

3.56 (1.05–12.09)

0.042

 No

 

1.00 (Reference)

  

1.00 (Reference)

 

WBC (cells/μL)

163

     

  > 10 × 103

 

4.95 (2.22–11.02)

<0.001

   

  ≤ 10 × 103

 

1.00 (Reference)

    

Overt DIC

164

     

 Yes

 

3.39 (1.76–6.55)

<0.001

   

 No

 

1.00 (Reference)

    

Capillary leakage

164

     

 Yes

 

9.36 (2.09–42.00)

0.003

   

 No

 

1.00 (Reference)

    

Creatine kinase (IU/L)

164

  

153

  

  > 500

 

10.81 (5.05–23.12)

<0.001

 

6.24 (2.10–18.49)

0.001

  ≤ 500

 

1.00 (Reference)

  

1.00 (Reference)

 

Blood sugar (mg/dL)

164

     

  ≥ 150

 

2.79 (1.27–6.10)

0.010

   

  < 150

 

1.00 (Reference)

    

Serum sodium (mmol/L)

164

  

153

  

  < 135 mmol/L

 

9.46 (4.60–19.43)

<0.001

 

7.81 (2.87–21.24)

<0.001

  ≥ 135 mmol/L

 

1.00 (Reference)

  

1.00 (Reference)

 

Microscopic hematuria

162

  

153

  

 Yes

 

10.51 (4.74–23.28)

<0.001

 

11.45 (3.76–34.82)

<0.001

 No

 

1.00 (Reference)

  

1.00 (Reference)

 

Time from bite to receiving antivenom (hours)

156

  

153

  

  ≥ 2

 

2.45 (1.20–5.02)

0.014

 

7.98 (2.06–30.92)

0.003

  < 2

 

1.00 (Reference)

  

1.00 (Reference)

 
  1. Abbreviations: CI confidence interval, DIC disseminated intravascular coagulation, OR odds ratio, WBC white blood cell