Table 1 Characteristics of the GN and non-GN patients in the cohort. Data are presented as mean ± standard deviation (SD), median (IQR) or count (frequency)

Number

288

1899

Median follow up (months)

39.0 (33.5–39.0)

39.0 (22.5–39.0)

Age (years)

58.9 ± 15.1

69.7 ± 11.7

<0.001

Male (%)

189 (66%)

1184 (62%)

0.3

Caucasian (%)

241 (84%)

1703 (90%)

<0.001

  Diabetes

-

777 (41%)

  Hypertension

-

823 (48%)

  PCKD

-

108 (6%)

  Other non-GN

-

252 (13%)

  IgA Nephropathy

61 (21%)

-

  FSGS

35 (12%)

-

  ANCA Vasculitis

21 (7%)

-

  Lupus Nephritis

13 (5%)

-

  Membranous Nephritis

9 (3%)

-

  GN Unspecified

149 (52%)

-

Diabetes (%)

58 (20%)

1025 (54%)

<0.001

CVD history (%)

<0.001

  No CVD

206 (72%)

998 (53%)

  Ischemic HD

33 (12%)

365 (17%)

  CHF

29 (10%)

215 (11%)

  Ischemic and CHF

20 (7%)

321 (17%)

Mean eGFR (ml/min/1.73 m²) ++/SD

27.1 ± 9.1

27.7 ± 8.9

0.3

eGFR categories (%)

0.1

  < 20 ml/min

81 (28%)

428 (23%)

  20–29

107 (37%)

757 (40%)

  > 30

100 (35%)

714 (40%)

uACR (mg/mmol)

59.5 [13.7–172.3]

14.4 [2.9–76.8]

<0.001

Systolic BP (mmHg)

131 ± 18

134 ± 20

<0.001

Diastolic BP (mmHg)

75 ± 12

70 ± 12

<0.001

Albumin (g/L)

40.0 ± 4.8

40.4 ± 4.2

0.08

Total cholesterol (mg/dL)

4.6 ± 1.2

4.2 + 1.1

0.03

Elevated Troponin I (% > LLD)

71 (25%)

714 (38%)

<0.001

CRP (mg/mL)

2.2 [0.9–5.3]

3.0 [1.2–6.9]

<0.001

ADMA

0.54 ± 0.94

0.55 ± 0.12

0.1

IL-6 (μg/L)

3.04 [1.00–5.80]

4.54 [1.00–7.25]

<0.001

NT-ProBNP (pg/mL) Pg/mL

273 [119–727]

511 [213–1485]

<0.001