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Table 3 Characteristics of matched GN and non-GN groups. Results are presented as mean ± standard deviation, median (IQR) or count (frequency)

From: Cardiovascular risk is similar in patients with glomerulonephritis compared to other types of chronic kidney disease: a matched cohort study

Variable

GN

Non-GN

P value

Number

272

272

 

Median follow up

39.0 (33.2–39.0)

39.0 (33.8–39.0)

 

Age (years)

60.5 ± 14

60.4 ± 14

0.9

Male

177 (65%)

177 (65%)

0.9

Caucasian

231 (85%)

242 (89%)

0.4

Cause of Kidney Disease

  Diabetic

-

49 (18%)

 

  Hypertensive

-

87 (32%)

 

  PCKD

-

44 (16%)

 

  Other non-GN

-

92 (34%)

 

  IgA

60 (22%)

-

 

  FSGS

33 (12%)

-

 

  ANCA Vasculitis

21 (8%)

-

 

  Lupus

13 (5%)

-

 

  Membranous Nephritis

9 (3%)

  

  GN unspecified

136 (50%)

  

Diabetes

57 (21%)

60 (22%)

0.7

CVD history

  

0.9

  No CVD

193 (71%)

201 (74%)

 

  Ischemic

33 (12%)

30 (11%)

 

  CHF

27 (10%)

25 (9%)

 

  Ischemic and CHF

19 (7%)

16 (6%)

 

eGFR (ml/min/1.73 m2)

27.0 ± 9.1

27.2 ± 9.1

0.8

eGFR categories

  

0.7

  < 20

76 (28%)

68 (25%)

 

  20–29

103 (38%)

109 (40%)

 

  > 30

93 (34%)

95 (35%)

 

ACR (mg/mmol)

58.7 [13.6, 170.2]

17.2 [3.6–90.0]

<0.001

Systolic BP (mmHg)

132 ± 19

131 ± 19

0.8

Diastolic BP (mmHg)

75 ± 12

74 ± 12

0.4

Statin

158 (58%)

147 (54%)

0.3

Albumin (g/L)

39.8 ± 4.8

41.1 ± 4.2

<0.001

Total cholesterol (mg/dL)

4.7 ± 1.2

4.5 ± 1.4

0.4

Troponin I (> LLD)

71 (26%)

68 (25%)

0.8

CRP (mg/mL)

2.4 [0.9–5.6]

2.4 [1.1–5.5]

0.6

ADMA

0.537 ± 0.094

0.534 ± 0.151

0.9

IL-6 (μg/L)

3.55 [1.00–6.02]

3.5 [1.00–5.27]

0.6

NT-ProBNP (pg/mL) Pg/mL

299 [121–799]

291 [107–757]

0.7

  1. Abbreviations: PCKD polycystic kidney disease, FSGS focal segmental glomerulosclerosis, CVD cardiovascular disease, CHF congestive heart failure, BP blood pressure, LLD lower limit of detection, ADMA asymmetric dimethylarginine, IL-6 interleukin 6, NT-Pro-BNP N-terminal pro-brain natriuretic peptide