Fig. 1From: Steroid-resistant nephrotic syndrome as the initial presentation of nail-patella syndrome: a case of a de novo LMX1B mutationRenal biopsy at the age of 7. Light microscopy only showed focal glomerular lesions (a) Periodic-Acid Schiff stain x400, (b) Periodic acid-methenamine-silver stain x400). Immunofluorescence showed slightly positive staining for IgM and C3 within glomerular segmental lesions (c). Electron microscopy revealed mild irregular thickening of the GBM and swollen podocytes (# in d) with partial foot process effacement (arrowhead in d). Neither electron-lucent areas within the GBM nor electron-dense deposits were detected (d)Back to article page