Skip to main content

Table 1 Study groups – demographic and clinical characteristics

From: Early urinary biomarkers of diabetic nephropathy in type 1 diabetes mellitus show involvement of kallikrein-kinin system

 

microalbuminuric

non-microalbuminuric

p

Cases (male/female)

11 (6/5)

14 (6/8)

0.57

DM duration (years)

26 (20–30)

22.5 (21–25)

0.78

Age (years)

35 (33–44)

35 (32–40)

0.76

BMI (kg/m2)

25.35 (21.97–28.6)

24.15 (23.51–24.96)

0.41

Systolic BP (mmHg)

138 (118–154)

138 (124–143)

1

Diastolic BP (mmHg)

84 (77–88)

79.5 (74–90)

0.62

Serum creatinine (μmol/l)

87 (81–116)

71.5 (61–76)

<0.01

eGFR (ml/min)a

77.8 (63.6–100.4)

108.8 (101.5–113.1)

<0.01

Albumin/creatinine ratio (mg/mmol)b

12.17 (5,56–15.15)

0.505 (0.43–0.7)

<0.0001

HbA1c

7.9% (6.9–8.5)

63 mmol/mol (52–69)

6% (5.3–7.1)

42 mmol/mol (34–54)

<0.01

Serum cholesterol (mmol/l)

4.6 (4.1–5.4)

5.4 (4.5–5.7)

0.13

Triglycerides (mmol/l)

1.21 (1.09–1.34)

0.88 (0.72–1.97)

0.38

  1. Data are given as medians (IQR), statistical significance was confirmed with Mann–Whitney rank sum test
  2. aeGFR was calculated by CKD-EPI formula
  3. bIn 9 non-microalbuminuric patients, urinary albumin was under the detection limit (<3 mg/l), here the albumin concentration was set arbitrarily to 3 mg/l