Table 3 Genotype and allele frequencies of IL 1β -511 in transplant recipients as a whole and grouped and controls
Genotypes | E1/E1 (%) | E1/E2 (%) | E2/E2 (%) | No. Of Alleles C/T |
|---|---|---|---|---|
Patients (n = 91) | 41 (45.1%) | 45 (49.4%) | 5 (5.5%) | 55/127 (30.2/69.8) |
Controls (n = 200) | 58 (29%) | 110 (55%) | 32 (16%) | 174/226 (43.5/56.5) |
OR at 95% CI | 2.01 (1.201–3.356) | 0.800 (0.487–1.315) | 0.305 (0.115–0.812) | 0.563 (0.387–0.817) |
RE (n = 30) | 18 (60%) | 11 (36.7%) | 01 (3.3%) | 13/47 (21.7/78.3) |
SGF (n = 61) | 22 (36.1%) | 35 (57.4%) | 4 (6.5%) | 43/79 (35.2/64.8) |
P – value and OR at 95% CI (RE vs SGF) | 0.031; OR = 2.66 (1.083–6.530) | 0.063; OR = 0.43 (0.175–1.057) | 0.885; OR = 0.491 (0.052–4.602) | 0.062; OR = 0.508 (0.248–1.042) |
Steroid responsive RE (n = 24) | 16 (66.6%) | 8 (33.33%) | 0 | 40/8 (83.3/16.6) |
Steroid Resistant RE (n = 6) | 3 (50%) | 2 (33.33%) | 1 (16.66) | 8/4 (66.66/33.3) |