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Table 1 Patient demographics and laboratory data

From: Relationship between serum bilirubin concentrations and diabetic nephropathy in Shanghai Han’s patients with type 1 diabetes mellitus

 

DN (n = 33)

Non-DN (n = 225)

P-value

Male: Female

16:17

111:114

0.98

Age (years)

54 (34.50–66)

49 (31–60)

0.06

Duration of diabetes (years)

13.92 (5.50–20)

4.56 (1–8)

<0.001**

BMI (kg/m2)

22.67 (21.85–22.75)

21.85 (17.75–33.65)

0.09

SBP (mmHg)

130 (120–140)

120 (110–125)

<0.001**

DBP (mmHg)

79 (70–80)

78 (70–80)

0.81

WHR

0.87 (0.85–0.94)

0.86 (0.83–0.88)

0.01*

FPG (mmol/L)

8.24 (5.71–11.47)

7.73 (6.18–10.70)

0.48

2hPG (mmol/L)

12.74 + 6.73

14.03 + 5.57

0.23

HbA1c (mmol/mol)

79 (62–95)

79 (60–105)

0.68

GA (%)

27.50 (21.50–31)

27.50 (23–34)

0.44

CRP (mg/L)

1.01 (0.66–3.87)

0.68 (0.27–2.86)

0.25

Uric acid (mg/dL)

328 (246.50–414.5)

272 (223–316.50)

<0.001**

Cr (mg/dL)

78 (60–99.50)

63 (52–74)

0.01*

Fasting C peptide (ng/mL)

0.19 (0.03–1.13)

0.29 (0.05–0.80)

0.56

30-min postprandial venous C peptide (ng/mL)

0.1 (0.03–0.96)

0.35 (0.05–1.17)

0.93

120-min postprandial venous C peptide (ng/mL)

0.08 (0.03–1.62)

0.48 (0.07–1.58)

0.64

Albumin (g/dL)

41 (37.50–43)

42.44 (40–45)

<0.001**

ALT (U/L)

16 (11–24.5)

17 (12–25)

0.56

AST (U/L)

18 (15–24)

19 (15–24)

0.42

γ-GT(U/L)

18 (16–23.50)

15 (12–22)

0.73

Total Bilirubin (mg/dL)

0.56 (0.43–0.68)

0.70 (0.58–0.89)

<0.001**

TC (mmol/L)

4.75 + 1.34

4.41 + 0.99

0.09

TG (mmol/L)

1.09 (0.87–1.62)

0.88 (0.70–1.17)

0.07

HDL-C (mmol/L)

1.28 (0.95–1.66)

1.27 (1.10–1.60)

0.59

LDL-C (mmol/L)

2.69 (2.18–3.36)

2.68 (2.16–3.39)

0.17

Haemoglobin (g/dL)

126 (109.50–136.5)

130 (74–171)

0.04*

24 h urinary microalbumin (mg/24 h)

196.67(49.27–1123.33)

7.01 (4.89–10.44)

<0.001**

Total GFR (mL/min)

81.75 (60.35–96.03)

98.95(86.95–107.20)

<0.001**

  1. Data are expressed as the means + standard deviation (SD) for normal distribution variables or as the median (interquartile range) for skewed distribution variables
  2. Abbreviations: DN diabetic nephropathy, T1DM type 1 diabetes mellitus, BMI body mass index, SBP systolic blood pressure, DBP diastolic blood pressure, WHR waist-to-hip ratio, FPG fasting plasma glucose, 2hPG 2 h postprandial glucose, HbA1c glycated haemoglobin A1c, GA glycated albumin, Cr creatinine, CRP C-reactive protein, ALT alanine aminotransferase, AST asparatate aminotransferase, γ-GT γ-glutamyltranspeptidase, TC total cholesterol, TG triglycerides, HDL-C high-density lipoprotein cholesterol, LDL-C low-density lipoprotein cholesterol, GFR glomerular filtration rate, OR odds ratio, 95% CI 95% confidence interval
  3. * P < 0.05, ** P < 0.01