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Table 5 Prevalence of DN in patients with T1DM according to quartiles of serum bilirubin concentrations

From: Relationship between serum bilirubin concentrations and diabetic nephropathy in Shanghai Han’s patients with type 1 diabetes mellitus

Bilirubin quartile

Prevalence (%)

Unadjusted

Adjusted

OR (95% CI)

P-value

OR (95% CI)

P-value

Q1 (n = 64)

21.90

1 (Referent)

 

Q2 (n = 76)

17.10

0.74 (0.32–1.71)

0.48

0.52 (0.19–1.41)

0.20

Q3 (n = 68)

7.40

0.28 (0.10–0.84)

0.02*

0.24 (0.07–0.82)

0.04*

Q4 (n = 50)

2.00

0.07 (0.01–0.58)

0.01*

0.11 (0.01–0.92)

0.02*

P trend for ORs

 

0.02*

 

0.04*

  1. Adjustment based on duration of diabetes, BMI, TG, Albumin, Haemoglobin and WHR
  2. Bilirubin quartiles: Q1, 0.20–0.60 mg/dL; Q2, 0.60–0.80 mg/dL; Q3, 0.80–1.00 mg/dL; Q4, 1.00–1.90 mg/dL
  3. OR odds ratio, 95% CI 95% confidence interval
  4. *P < 0.05