From: Nephrotoxicity-induced proteinuria increases biomarker diagnostic thresholds in acute kidney injury
Baseline characteristics | No-albuminuria (ACR < 30 mg/g) (n = 16) | Albuminuria (ACR ≥ 30 mg/g) (n = 34) | p |
---|---|---|---|
Age (years) | 23 (19–35) | 25 (19–32) | 0.97 |
Male gender (%) | 60 | 50 | 0.5 |
Weight (kg) | 50 (45–55) | 50 (39–60) | 0.65 |
Volume ingested (ml) | 10 (5–30) | 20 (20–50) | 0.05 |
Time to admission (hours) | 4 (2–6) | 3.5 (2–7.5) | 0.98 |
Pulse (beats/min) | 80 (78–88) | 82 (80–89) | 0.50 |
BP systolic (mm Hg) | 120 (110–120) | 110 (110–120) | 0.18 |
BP diastolic | 80 (70–80) | 70 (70–80) | 0.52 |
sCr (mg/dl) | 0.7 (0.5–0.8) | 0.9 (0.7–1.3) | 0.006 |
sCysC (mg/l) | 0.7 (0.6–0.8) | 0.7 (0.6–0.8) | 0.53 |
Maximum serum paraquat (ng/ml/24 h) | 20 (10–120) | 640 (140–1400) | 0.0006 |
Functional-AKI (%) | 8 (50%) | 29 (85%) | 0.007 |
Death (n) | 0 | 12 | 0.006 |